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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A RADIOGRAPHIC AID TO PROTON THERAPY

    SBC: Acctek Associates, Inc.            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS PROGRAM IS THE DEVELOPMENT OF THE CAPABILITY OF PRECISION PROTON RADIOGRAPHY WITH ACCELERATOR SYSTEMS DESIGNED OR USED FOR PROTON RADIATION THERAPY. A PROTON RADIOGRAPH TAKEN IMMEDIATELY PRIOR TO RADIATION TREATMENT COULD GIVE INCREASED CONFIDENCE IN THE ADEQUACY OF THE TREATMENT PLAN, CHECK ALIGNMENT WITH TUMOR SITE, AND CONFIRM READINESS AND CALIBRATION OF THE ENT ...

    SBIR Phase I 1991 Department of Health and Human Services
  2. LASER SYSTEM FOR PHOTOTHERMAL INTRASTROMAL KERATOPLASTY

    SBC: Antropix Corpon            Topic: N/A

    WE WILL DEVELOP A LASER SYSTEM THAT IS SUITABLE FOR PERFORMING PHOTOTHERMAL INTRASTROMAL KERATOPLASTY TO CORRECT OCULAR REFRACTIVE ERRORS. LASER PARAMETERS (WAVELENGTH, IRRADIANCE, AND IRRADIATION TIME) AND DELIVERY/GEOMETRY PARAMETERS (BEAM PROFILE, SPOT SIZE, PATTERN, AND SLEW RATE) SHALL BE OPTIMIZED FOR TREATMENT OF MYOPIA, HYPEROPIA, AND ASTIGMATISM. IN THE PHASE I PROGRAM RESEARCH, A PROTOTY ...

    SBIR Phase I 1991 Department of Health and Human Services
  3. ISOLATION AND EXPRESSION OF CDNA CLONES FOR RIF

    SBC: Argus Pharmaceuticals Inc            Topic: N/A

    CYTOTOXIC ACTIVATED MACROPHAGES SECRETE SOLUBLE FACTORS THAT HAVE A VARIETY OF EFFECTS ON TUMOR CELLS. INCLUDED IN THE TUMOR CELL RESPONSE ARE THE INHIBITION OF MITOCHONDRIAL RESPIRATION AND INHIBITION OF DNA SYNTHESIS. A MONOKINE CALLED RIF, WHICH WAS FOUND TO REPRODUCE THESE EFFECTS IN VITRO, HAS BEEN CHARACTERIZED. THE ISOLATION AND VERIFICATION OF THE CDNA FOR RIF IS THE PRIMARY FOCUS OF THIS ...

    SBIR Phase I 1991 Department of Health and Human Services
  4. ANTI-HSV-1 ACTION OF TRIPLEX FORMING OLIGONUCLEOTIDES

    SBC: Aronex Pharmaceuticals, Inc            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  5. MICROPROCESSOR SELF-TONOMETER FOR HOME IOP MONITORING

    SBC: Assurance Technologies Inc.            Topic: N/A

    IN TREATING GLAUCOMA, THE CLINICIAN ATTEMPTS TO LOWER THE INTRAOCULAR PRESSURE (IOP) BUT, BECAUSE IT IS NOT CONSTANT, A SINGLE MEASUREMENT DURING A VISIT TO THE OPHTHALMOLOGIST MAY BE UNRELIABLE. THE MEASUREMENT OF THE IOP AT THE PATIENT'S HOME HAS BEEN ADVOCATED BUT HAS BEEN HAMPERED BY THE LACK OF AN INSTRUMENT THAT CAN BE USED RELIABLY AND SAFELY BY THE PATIENT ALONE. A SELF-TONOMETER, RECENTLY ...

    SBIR Phase II 1991 Department of Health and Human Services
  6. AUTOANALYZER FOR FIVE HEMOGLOBIN SPECIES

    SBC: AVOX SYSTEMS, INC.            Topic: N/A

    THIS PROJECT WILL DEVELOP A SPECTROPHOTOMETRIC INSTRUMENT TO MEASURE THE TOTAL HEMOGLOBIN CONCENTRATION OF WHOLE BLOODAND THE RELATIVE CONCENTRATIONS OF OXY-, DEOXY-, CARBOXY-, MET-, AND SULFHEMOGLOBIN. THE CHIEF STRATEGY IS TO MAKE BEER'S LAW APPLY TO WHOLE BLOOD BY MINIMIZING THE EFFECTS OFLIGHT SCATTERING AND TO EMPLOY MATRIX MATH TECHNIQUES TO SOLVE FOR THE FIVE HEMOGLOBIN CONCENTRATIONS FROM ...

    SBIR Phase II 1991 Department of Health and Human Services
  7. CAPILLARY-TUBE HEMOGLOBINOMETER-OXIMETER

    SBC: AVOX SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  8. STROKE REHABILITATION DEVICE

    SBC: Axonix Inc            Topic: N/A

    WE SEEK TO DEVELOP A VIABLE, COST-EFFECTIVE, SAFE STROKE REHABILITATION DEVICE BASED UPON THE ELECTRONIC STIMULATION OF STROKE-AFFECTED LIMBS. A KEY PROBLEM IN STROKE REHABILITATION THERAPY IS TO HAVE THE STROKE IMPAIRED LIMBS EXERCISED ENOUGH TO AVOID MUSCLE ATROPHY OR DEFORMATION FROM CONTRACTURES. IN GENERAL, PHYSICAL THERAPISTS DO NOT HAVE SUFFICIENT TIME TO WORK WITH THE PATIENT TO PROVIDE TH ...

    SBIR Phase I 1991 Department of Health and Human Services
  9. INTERACTIVE MEDICAL IMAGE ANALYSIS WORKSTATION

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  10. SALMONELLA CONTROL ON POULTRY USING A DISINFECTANT DIP

    SBC: Biomedical Development Corporation            Topic: N/A

    CURRENTLY, POULTRY PRODUCTS WHICH ARE PROCESSED AND DISTRIBUTED IN A NON-COOKED FORM, MAY CONTAIN SIGNIFICANT NUMBERS OF PATHOGENIC BACTERIA SUCH AS SALMONELLA, LISTERIA AND CAMPYLOBACTER. POULTRY PROCESSING TECHNOLOGY HAS NOT, AT THIS TIME, DEVELOPED A SYSTEM OF EVISCERATION THAT DOES NOT CONTAMINATE THE CARCASS TO SOME EXTENT. TECHNOLOGY TO ELIMINATE THESE CONTAMINATING PATHOGENS FROM THE CARCAS ...

    SBIR Phase I 1991 Department of Health and Human Services

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