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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Ultra-High-Density Arrays for Genome Research

    SBC: Accelerator Technology Corporation            Topic: N/A

    We will develop porous silicon based detector chips for the identification of biomoleculefragments. Patches of porous silicon on a silicon wafer act as active sieves, loaded with taggingmolecules, where during passage through it biomolecule fragments are identified by their response afterattachment of a tag to a modulated electric field applied across the porous patch. This technique, ifsuccessful ...

    SBIR Phase I 1994 Department of Health and Human Services
  2. Development of High-Speed Nucleic Acid Hybridization

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    Nucleic acid hybridization reactions are at the heart of a number of powerful assays used in molecular biology research and increasingly in diagnostic applications. Hybridization reactions typically require long incubation times, i. e. overnight. Recent work has demonstrated that a ribonucleoprotein and certain cationic detergents can increase hybridization rates several thousand fold such that th ...

    SBIR Phase II 1994 Department of Health and Human Services
  3. Ultrasensitive Nonisotopic Detection of RNA

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  4. Nursing Facility Management Software to Monitor Quality of Care

    SBC: Austin Data Management Associa            Topic: N/A

    The project will design personal computer software that is usable to nursing facility managers and others, such as health care professionals, consumer advocates, and placement specialists. It will make quality of care information available and analyze service pattern and staffing.

    SBIR Phase II 1994 Department of Health and Human Services
  5. Development of Accurate Test Kits for Malabsorption

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    Accurate measurement of gastrointestinal absorption of various substances is important in bothresearch and diagnosis. In many cases, the acceptable general approach is the balance procedure. Thisprocedure suffers from the requirement for complete collection of stools over an extended period oftime. This limitation prevents widespread use of this otherwise desirable approach. The investigatorspropo ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. Micron Resolution Volume-Computed Tomography

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    Instrumentation that can provide microstructural characterization of medical grade polymers,fabrics, and composite materials is the proposed research's long term goal. One micron resolutionvolume computed tomography of test specimens can now be demonstrated by combining anNIST-developed x-ray microscope with BIR's volume CT capability. Micro VCT will be a valuable toolin the development of new med ...

    SBIR Phase I 1994 Department of Health and Human Services
  7. Fiber Optic Sensor for Cardiac Magnetic Field

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    We will adapt a non-cryogenic magnetic field sensor previously developed for defense purposesand apply it to magnetocardiography (MCG), the measurement of magnetic fields induced by electricalcurrents in the heart. As a single non-invasive sensor, this unit would have similar applications to theelectrocardiograph. When these units are assembled into a spatial array, the magnetic field can bemeasur ...

    SBIR Phase I 1994 Department of Health and Human Services
  8. COLD STERILANT FOR DELICATE MEDICAL INSTRUMENTS

    SBC: Biomedical Development Corporation            Topic: N/A

    WE ARE DEVELOPING A COLD STERILIZATION TECHNOLOGY THAT IS RAPIDLY BIOCIDAL AGAINST FUNGI, VIRUSES, BACTERIA AND BACTERIAL SPORES, BUT IS NEITHER TOXIC NOR MUTAGENIC TO HIGHER ORGANISMS.THE BIOCIDAL ACTIVITY REMAINS POTENT FOR LONG PERIODS OF TIME, IS NON-CORROSIVE TO 200 AND 400 GRADE STAINLESS STEEL INSTRUMENTS, DOES NOT STAIN OR SMELL, AND CAN BE PRODUCED FOR LESS THAN 1/50TH THE COST OF PRESENT ...

    SBIR Phase II 1994 Department of Health and Human Services
  9. Locating Device for Wandering Alzheimer Patients

    SBC: Biomedical Development Corporation            Topic: N/A

    We will develop and test a locating device worn on a person's body that can be used to locatepatients with dementia who have wandered away. Current technology used to protect wanderingpatients focuses on alerting caregivers to patient exits, but does not assist in locating patients once theyhave departed. Phase I will assess caregiver interest in this type of locating device, develop and test ahou ...

    SBIR Phase I 1994 Department of Health and Human Services
  10. Dialysis Disinfectant Replacing Formaldehyde, Sterilants

    SBC: Biomedical Development Corporation            Topic: N/A

    Formaldehyde is a common disinfecting agent in dialyzer membrane reuse procedures. Since formaldehyde is carcinogenic, toxic and malodorous, any safe, cost-effective alternative would be a marketable an medical success. The long-term objective is to benefit patient care, employee safety, and cost effectiveness by establishing an economically competitive, non-toxic, market alternative to formaldehy ...

    SBIR Phase II 1994 Department of Health and Human Services

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