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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Ultra-High-Density Arrays for Genome Research

    SBC: Accelerator Technology Corporation            Topic: N/A

    We will develop porous silicon based detector chips for the identification of biomoleculefragments. Patches of porous silicon on a silicon wafer act as active sieves, loaded with taggingmolecules, where during passage through it biomolecule fragments are identified by their response afterattachment of a tag to a modulated electric field applied across the porous patch. This technique, ifsuccessful ...

    SBIR Phase I 1994 Department of Health and Human Services
  2. Ultrasensitive Nonisotopic Detection of RNA

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    N/A

    SBIR Phase I 1994 Department of Health and Human Services
  3. Development of Accurate Test Kits for Malabsorption

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    Accurate measurement of gastrointestinal absorption of various substances is important in bothresearch and diagnosis. In many cases, the acceptable general approach is the balance procedure. Thisprocedure suffers from the requirement for complete collection of stools over an extended period oftime. This limitation prevents widespread use of this otherwise desirable approach. The investigatorspropo ...

    SBIR Phase I 1994 Department of Health and Human Services
  4. Micron Resolution Volume-Computed Tomography

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    Instrumentation that can provide microstructural characterization of medical grade polymers,fabrics, and composite materials is the proposed research's long term goal. One micron resolutionvolume computed tomography of test specimens can now be demonstrated by combining anNIST-developed x-ray microscope with BIR's volume CT capability. Micro VCT will be a valuable toolin the development of new med ...

    SBIR Phase I 1994 Department of Health and Human Services
  5. Fiber Optic Sensor for Cardiac Magnetic Field

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    We will adapt a non-cryogenic magnetic field sensor previously developed for defense purposesand apply it to magnetocardiography (MCG), the measurement of magnetic fields induced by electricalcurrents in the heart. As a single non-invasive sensor, this unit would have similar applications to theelectrocardiograph. When these units are assembled into a spatial array, the magnetic field can bemeasur ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. Locating Device for Wandering Alzheimer Patients

    SBC: Biomedical Development Corporation            Topic: N/A

    We will develop and test a locating device worn on a person's body that can be used to locatepatients with dementia who have wandered away. Current technology used to protect wanderingpatients focuses on alerting caregivers to patient exits, but does not assist in locating patients once theyhave departed. Phase I will assess caregiver interest in this type of locating device, develop and test ahou ...

    SBIR Phase I 1994 Department of Health and Human Services
  7. Ibogaine and Metabolites in Urine and Plasma

    SBC: Cedra Corp.            Topic: N/A

    We will develop and validate a sensitive and inexpensive analytical procedure for the analysisof ibogaine and its potential metabolites in biological fluids. The work will involve applying CEDRAproprietary analytical technology for the analysis of chemically similar compounds (indoles). Thistechnology was recently applied at CEDRA resulting in the analysis of iobgaine to a level of 250 pg/mlin pla ...

    SBIR Phase I 1994 Department of Health and Human Services
  8. Novel Compounds for the Treatment of Memory Disorders

    SBC: Chicago Institute For Neuro            Topic: N/A

    We have generated a monoclonal antibody, B6B21, and have shown that it significantlyenhances acquisition rates in hippocampus-dependent trace eyeblink conditioning in rabbits, halving thenumber of trials required to reach 80% conditioned responses. Previous studies, with a variety of modelsystems, have shown that B6B21 acts as a partial ago mst at the glycine site of the N-methyl-D-aspart-ate rece ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. Assay of Carcinogenic Potential of Chemicals

    SBC: Dermigen, Inc.            Topic: N/A

    Transgenic mice expressing activated oncogens offer considerable potential as rapid andsensitive models to identify and quantify the activities of environmental chemicals that act at one ormore steps in the carcinogenic process. The research will focus on two newly developed lines oftransgenic mice, HK1.ras and HK1.fos, that offer particular promise for the rapid and sensitiveidentification and qu ...

    SBIR Phase I 1994 Department of Health and Human Services
  10. Interactive Media for Early Detection of Skin Cancers

    SBC: EDUMEDIA, INC.            Topic: N/A

    Elderly women and men are at higher risk for developing skin cancers, as a result of theirincreased cumulative exposure to ultraviolet radiation, and their depressed immune system functioningrelative to younger persons. Interactive multimedia materials providing information about skin lesionsand teaching early detection skills will be developed for target groups of elderly. Social cognitiveprincip ...

    SBIR Phase I 1994 Department of Health and Human Services
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