Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. SBIR PHASE I, TOPIC 239 HIGH-THROUGHPUT SELECTION OF APTAMERS AGAINST CANCER BIOM

    SBC: Accacia International LLC            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human Services
  2. T7 RNA polymerase engineering and RNA amplification

    SBC: Accacia International LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Expanding use of microarray systems for global gene expression profiling is leading biological research, providing diagnostic and prognostic value to physicians and facilitating target discovery during drug and vaccine development. There is strong interest in extending this microarray capability to more RNA-limited material to the point that a single cell can b ...

    STTR Phase II 2007 Department of Health and Human Services
  3. Ultra-High-Density Arrays for Genome Research

    SBC: Accelerator Technology Corporation            Topic: N/A

    We will develop porous silicon based detector chips for the identification of biomoleculefragments. Patches of porous silicon on a silicon wafer act as active sieves, loaded with taggingmolecules, where during passage through it biomolecule fragments are identified by their response afterattachment of a tag to a modulated electric field applied across the porous patch. This technique, ifsuccessful ...

    SBIR Phase I 1994 Department of Health and Human Services
  4. Development of a Lightweight, Durable, Adjustable Composite Backrest

    SBC: ACCESSIBLE DESIGNS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We have designed a prototype lightweight, sturdy, user adjustable ergonomically designed backrest support for ultralight weight wheelchairs that will provide necessary postural support and provide a variety of positions to ease dressing, propulsion, and seated comfort. The backrest will improve user comfort, function, and posture during multiple activities of ...

    SBIR Phase I 2007 Department of Health and Human Services
  5. Accelerated Discovery and Development of New Pain Therapeutics

    SBC: AESTUS THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): More than 25 million people in the United States suffer from neuropathic pain. Currently available drugs include opioids, anti-epileptics, topicals such as lidocaine, NMDA antagonists, and tricyclic antidepressants, none of which achieve clinical significance greater than 50%. To address this problem of significant clinical need and poor clinical significance, ...

    SBIR Phase I 2007 Department of Health and Human Services
  6. Treatment of Sepsis with Talactoferrin

    SBC: AGENNIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Severe sepsis is a major cause of morbidity and mortality throughout the world. It is the leading cause of death in non-coronary intensive care units (ICUs) in the United States, with more than 750,000 cases occurring e very year. This means that in the United States, more than 500 patients die from severe sepsis every day, with 28% to 50% of the patients succu ...

    SBIR Phase I 2007 Department of Health and Human Services
  7. Networked Portable Personal Aerosol Sensors

    SBC: AGINOVA, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Environmental factors such as toxins and pollutants are known to have a strong correlation to the incidence of various common human diseases. However, a critical shortcoming in quantitative studies of the correlation is the lack of robust, reliable, and inexpensive devices to measure the personal exposure to pollutants. Further, studies over extended periods of ...

    SBIR Phase I 2007 Department of Health and Human Services
  8. Ultrasound monitored HIV rapid test

    SBC: Allied Innovative Systems LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of the proposed research is to develop a novel quantitative particle agglutination technology for improving the performance of detection of human immunodeficiency virus (HIV) antibody in body fluids. The conventional particle agglutination assays have serious drawbacks such as limited sensitivity, long time of incubation, subjectivity and la ...

    SBIR Phase II 2007 Department of Health and Human Services
  9. Quantitative analysis of RhD antibodies

    SBC: Allied Innovative Systems LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of the proposed research is to develop sensitive, specific and quantitative enzyme-linked immunosorbent assays (ELISA) for (1) measuring anti-RhD (anti-D) antibodies in patients at risk for Hemolytic Disease of the Newborn (HDN), (2) screening individuals who receive anti-D for prophylaxis of HDN, (3) qualitative assessment of anti-D preparat ...

    SBIR Phase II 2007 Department of Health and Human Services
  10. Development of High-Speed Nucleic Acid Hybridization

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    Nucleic acid hybridization reactions are at the heart of a number of powerful assays used in molecular biology research and increasingly in diagnostic applications. Hybridization reactions typically require long incubation times, i. e. overnight. Recent work has demonstrated that a ribonucleoprotein and certain cationic detergents can increase hybridization rates several thousand fold such that th ...

    SBIR Phase II 1994 Department of Health and Human Services
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