Award Data

Autonomous planning of space-based unmanned craft is at the cutting edge of science and technology. Problems associated with planning arise when multiple independent agents each on separate spacecraft must work in a coordinated fashion for a combined mission. This proposal examines the ramifications of cooperating and independent autonomous agents controlling unmanned craft toward a common cause. ...

Understanding that saving weight without sacrificing performance on a vehicle is important, the objective of this program is to continue to demonstrate advanced lightweight materials that can have multi-functional capability and be discretely made into parts for DLA. Many applications will have specific requirements of high thermal conductivity, low thermal conductivity, radiation resistance, Mod ...

Great strides have been made in developing diagnostic systems for detecting and identifying specific pathogens and their toxins. However, these systems may be too specific and unable to detect newly emerging pathogens whose immunological or genetic profile is different than the normal complement of pathogens. The ideal system in an isolated environment such as a spacecraft would be one that provid ...

Conventional fluorescence-activated cell sorters (FACSs) are widely used to study eukaryotic cell populations. Although they provide impressively efficient sorting, they are costly, mechanically complex, and require large sample volumes and trained personnel for operation and maintenance. In addition, the footprint per unit separation is considerable and they typically require large input populati ...

The occurrence of causative agents such as Cryptosporidium parvum and other pathogens in water supplies presents a critical issue. Transmitted through water and animals, these organisms provide a reservoir of infection, which results in the excretion of the environmentally stable cysts or oocysts that are impervious to inactivation by many drinking water disinfectants. Cryptosporidium infections a ...

The occurrence of causative agents such as Cryptosporidium parvum and other pathogens in water supplies presents a critical issue. Transmitted through water and animals, these organisms provide a reservoir of infection, which results in the excretion of the environmentally stable cysts or oocysts that are impervious to inactivation by many drinking water disinfectants. Cryptosporidium infections a ...

Agve BioSystems in collaboration with Carl A. Batt propose to develop decon-nanoparticles which will leverage ongoing opportunities in enzyme engineering and the fabrication of functionalized magnetic nanoparticles. Enhanced performance will be engineered into the system to improve the catalytic degradation of chemical agents. Through an iterative process optimizing the particles and the enzyme ...

AM Biotechnologies (AM) will develop a diagnostic system in response to SBIR Topic X10.01 Reusable Diagnostic Lab Technology that will simultaneously detect and quantify numerous protein biomarkers with excellent sensitivity. AM will enhance the current clinical gold standard immunoassay methodology by using its proprietary bead-based aptamer selection process to select dithiophosphate backbone-m ...

Thermoelectric (TE) generators/refrigerators have the advantages of lack of moving parts, quiet operation, and flexibility in deployment, but their use has been limited because of their relatively low conversion efficiency. Two major loss components are conductive (phonon) heat transfer through the TE lattice and parasitic losses at fabrication interfaces. Shock wave consolidation of thermoele ...

This Phase I program proposes to synthesize novel nanoengineered ultra low out gassing elastomers and formulate high temperature capable flexible thermal control coatings as well as adhesives based on the proposed chemistries that are stable in various space environments. We have envisioned nano-engineered clusters and the innovative synthesis of the poly carborane-polysiloxanes, to surpass the pe ...