Award Data

Project Summary Falls are the leading cause of injurieshospital visitsnursing home admissionsand reduced quality of life for people with neurological disordersAlthough there is consensus that impaired mobility is the basis for most fallsit is very di cult to evaluate these complex abilities outside a laboratory settingBrief clinical examinations do not accurately re ect dailyfunctional mobility in ...

DESCRIPTIONprovided by applicantComprehensive bio psychosocial screeningwhich covers not only physical symptoms and psychosocial issuesbut also practical concerns such as transportationfinanceswork and childcareoffers the true opportunity to maximize the benefits of medical care and social support to patients and their families while enhancing operational efficiency and resource management for hea ...

DESCRIPTION provided by applicant Over percent of the U S population is currently overweight or obese percent are obese Obesity is a primary cause of numerous chronic diseases including type II diabetes cancer heart disease and the metabolic syndrome Behavioral weight loss interventions have successfully resulted in significant clinical improvements in weight percent weight lo ...

Abstract High risk human papillomaviruses HPV cause cervical cancer the second most common neoplasm among women globally and a large proportion of oropharyngeal cancers Although prophylactic vaccines to HPV are effective they have no therapeutic effect and thus do not benefit the millions of individuals already infected Thus there is both a medical need and a commercial opportunity for a HP ...

DESCRIPTIONprovided by applicantThe goal of this small business innovation research grant is to develop and commercialize a highly accurateminimally invasive risk stratification technique for colorectal cancerCRCthat is simple enough to be performed by the primary care provider during an annual physical examAlthough existing guidelines recommend CRC screening for all patients over agertmillion Ame ...

Abstract Stroke is a leading cause of morbidity and mortality in the United States However less than of patients are eligible for the current approved interventions of tissue plasminogen activator or thrombectomy We seek to develop new therapeutics to reduce the extent of damage and functional impairment resulting from ischemic injury to the brain an area of significant unmet medical need ...

Project Summary! This STTR Phase II project continues the development of the Newborn Acuity Cardstm and the Newborn Contrast Cardstm Together these Newborn Cards form a new clinical test of visual acuity and contrast sensi tivity for use on newborn full term and preterm infants The stimuli are square wave gratings which the examiner presents to the infant in a fixation and following protocol ...

Ebola EBOV and Marburg MARV viruses belong to the family Filoviridae and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction with an incubation period of days Because of the safety concerns these viruses are designated as the biosafety level agents Currently there is no effective vaccine or therapeutic treatment against filoviral infection and pathogenes ...

DESCRIPTION provided by applicant Stroke the leading cause of disability cognitive impairment and death in the US imposes significant financial and personal burden The residual effects of stroke affect many aspects of life not addressed by traditional rehabilitation treatments In particular persons with mild stroke typically defined as a stroke with no or sligh motor impairment and a high ...

DESCRIPTIONprovided by applicantThis Phase I II Fast Track application is being re submitted under the NHLBI Small Business Topics of Special Interest for Fiscal YearHLSCertain life saving interventions such as cardiopulmonary bypassCPBextracorporeal membrane oxygenationECMOor ventricular assist deviceVADpump require the use of high dose heparin to maintain blood flow through the devices and or to ...