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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Formulation and testing of an entirely wood-based exterior insulation board for the high-performance building market

    SBC: GO Lab Inc.            Topic: 17NCER6B

    The goal of this project is the formulation a rigid, insulating, low-density wood composite, with physical and thermal properties comparable to fossil fuel derived foams. _x000D_ _x000D_ To achieve energy conservation standards mandated by certification agencies such as Passive House and LEED, high performance buildings require multiple shells of insulation – an inner shell that contains electri ...

    SBIR Phase I 2018 Environmental Protection Agency
  2. Method for accurate retinal oxygen metabolic rate extraction

    SBC: OPTICENT, INC.            Topic: N

    PROJECT SUMMARY DR is a secondary complication of diabetes and a leading cause of blindness in the world Although it is well known that DR is driven by ischemia the current grading of DR severity is based only on structural alterations such as the presence of abnormal retinal microvasculature in non proliferative DR and angiogenesis in proliferative DR As a result when their diagnosis is first ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Wireless implantable optofluidic systems for programmed pharmacology and optogenetics

    SBC: Neurolux, Inc.            Topic: 101

    Project Summary Abstract Diseases of the central and peripheral nervous systems affect the quality of life of millions of people worldwide Progress in understanding the function of neural networks and in developing associated insights into the underlying causes of these diseases can be accelerated by advances in techniques and methodologies for neuroscience research Collaborative efforts between ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A real time cost effective accurate UV measurement and sun protection system to prevent and reduce the incidence of sunburn in high risk consumers

    SBC: WEARIFI, INC.            Topic: 100

    PROJECT SUMMARY ABSTRACT The US Surgeon General reports that skin cancer is the most common type of cancer in the US The number of Americans who have had skin cancer at some point over the last three decades is estimated to exceed all other cancers combined There are more than new cases of melanoma each year resulting in more than deaths Reports indicate that nearly of skin c ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Faraday a Novel Automated Peritoneal Dialysis Device with Dialysate Customization

    SBC: Simergent, LLC            Topic: 400

    PROJECT SUMMARY There are currently over patients on peritoneal dialysis PD around the globe Clinical outcomes are dictated largely by the dextrose and sodium concentrations used in each session However the state of the art in APD systems is woefully deficient clinicians must choose from only dialysate dextrose concentrations available and have no choice for sodium concentration W ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Study of the New HDAC i SW as a Treatment for Alzheimer's Disease and Other Tauopathies

    SBC: Starwise Therapeutics LLC            Topic: NIA

    ABSTRACT Alzheimerandapos s and other tauopathies are medical problems growing to historical proportions that threaten the long term viability of medical care systems world wide Alzheimerandapos s costs today are of the US GDP and growing as the population ages Effective disease modifying treatments have yet to be developed A number of drugs in clinical testing target amyloid but very fe ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A Safer Cardiac Abuse Deterrent Formulation of Methadone

    SBC: ACADEMIC PHARMACEUTICALS INC            Topic: NHLBI

    Project Summary Methadone is a synthetic opioid used to treat pain and as maintenance therapy for opiate addicted individuals Methadone does not have the euphoric properties of morphine and thus is less addictive Its use in the treatment of both acute and chronic pain thus offers advantage However limiting methadone s clinical use is its prolongation of the cardiac cell s repolarization time ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. AN HDAC APPROACH TO RETT SYNDROME

    SBC: Starwise Therapeutics LLC            Topic: NICHD

    Disease modifying therapies are needed for the treatment of Rett syndrome RTT as there are no current medications that get to the core of disease pathology Our ongoing work on the design of selective HDAC inhibitors HDAC i offers a truly innovative approach to the possible treatment of RTT as it begins to tackle cellular deficits we have identified that arise due to improper MeCP function ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Prognosis an interactive digital public health and epidemiology adventure

    SBC: RESILIENT GAMES STUDIO, LLC            Topic: OD

    Project Abstract The proposed Phase I STTR project will develop the serious game Prognosis and its supporting website to improve systems thinking and problem solving through learning about public health and epidemiology Prognosis is a simulation game that focuses on the population health of the fictional city Hexacago Through game play players will learn how multiple ambient citywide systems ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. SampleStream A Radically Simplified Platform for Protein Sample Preparation

    SBC: Integrated Protein Technologies, Inc.            Topic: 200

    Abstract The analysis of proteins intact or following digestion via mass spectrometry has the potential to revolutionize human health and wellness by identifying highly correlative markers for human disease and characterizing protein based drugs Unfortunately the high cost of mass spectrometric protein analyses has presented a barrier to their routine deployment in medical research diagnosti ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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