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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Methods for Fast and Efficient Oxygen Imaging
SBC: O2M TECHNOLOGIES LLC Topic: 102Abstract Intermittent or acute/cyclic hypoxia in tumors, with frequencies between a few cycles per minute to hours, is receiving increased attention because this type of hypoxia has been reported to have an influence on tumor malignancy as well as treatment resistance via increased expression of pro-survival pathways. Fast oxygen imaging methods are needed for the measurement of acute tumor hypoxi ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Image-based risk assessment to identify women at high-risk for breast cancer
SBC: WAVED MEDICAL LLC Topic: NCI7. PROJECT SUMMARY Breast cancer is the most common cancer worldwide and the most common cancer diagnosed in American women. While there has been good progress regarding detection and treatment methods, breast cancer remains the primary cause of death from malignant tumors. Hence, there is a critical need for the development of novel predictive and prognostic factors. Risk assessments are currentl ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Seaweed-based bioplastic replacement for commercial lobster fishing gear.
SBC: VIABLE GEAR LLC Topic: 93Viable Gear will provide proof-of-concept for a seaweed-based bioplastic to be used in manufacturing a compostable biotwine for marine equipment, designed to replace petroleum-based plastics. This addresses NOM-SBIR research topic area 9.3, The Changing Ocean - specifically to "support increased protection and restoration of marine and coastal habitats to enhance vital ecosystems", by helping decr ...
SBIR Phase I 2023 Department of CommerceNational Oceanic and Atmospheric Administration -
AeroLite Sense: Atmospheric Aerosols and Particulates Observations from the Stratosphere
SBC: STRATOSOLUTIONS INC Topic: 91The long endurance “StratoSonde” lighter-than-air, uncrewed system combines a low-cost, 5day endurance StratoSonde supports up to 10 micro-dropsondes, which when released from the HAB, descend safely through the entire atmospheric column under a ribbon drogue while reporting observations directly back to the HAB. This project will assess the feasibility of integrating a disposable miniature ae ...
SBIR Phase I 2023 Department of CommerceNational Oceanic and Atmospheric Administration -
A point-of-care salivary cytokine test for early detection of oral cancer
SBC: GLUCOSENTIENT INC Topic: 100Project Summary / AbstractOral cancer is the 6th most common cancer globally with ~ 350,000 new cases and claiming ~ 180,000 lives annually. Common risk factors include smoking and alcohol consumption. However, other local habits, such as khat chewing, can cause significantly higher regional higher prevalence (up to 40% of all cancer cases in some Asian countries). Currently, identification and di ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
SMALL MOLECULE THERAPEUTIC FOR ALZHEIMER'S DISEASE
SBC: SOMATOLYNK, INC. Topic: NIAAn estimated one out of eight individuals over the age of 65 has Alzheimer’s disease (AD), with a prevalence of 1-in-3 for those over age 85. There are approximately 5.8 million people in the USA with AD, with a global projection of over 150 million by 2050. There remains a lack of effective treatment to halt disease progression. Somatostatin receptor-4 (SSTR4) represents an innovative and viabl ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Mature brain organoid platform for therapeutic screening for ALS/FTD
SBC: SYNAPTICURE INC Topic: 105Abstract Synapticure is developing a novel patient-derived 3D platform for high-fidelity modeling and screening of TDP- 43 proteinopathy and associated biomarkers for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Synapticure’s mature brain organoids (mbOrgs) are composed of key neural cells derived from patient- induced pluripotent stem cells (iPSCs) and are custom assem ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Selective Activators of Nrf2 for Neurodegenerative Disease
SBC: GROVE BIOPHARMA, INC. Topic: 105Protein-like polymers (PLPs) are next generation biotherapeutics with the potential to improve treatment outcomes for patients suffering from devastating neurodegenerative diseases. We have developed a lead PLP that disrupts the Keap1-Nrf2 intracellular protein-protein interaction (PPI) that restricts the therapeutic activity of Nrf2 (nuclear factor-erythroid factor 2-related factor 2), a validate ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of A Novel Nanoparticle Biosensor for Rapid, Point-of-Care Sepsis Diagnosis and Risk Assessment
SBC: NAMI DIAGNOSTICS LLC Topic: NIAIDAbstract. In the United States, about 1.7 million adults affected by sepsis annually, which leads to more than 270,000 deaths per year. If sepsis cannot be diagnosed and treated early, it not only causes high morbidity and mortality rates, but also poses a major burden to the healthcare system since septic patients are generally hospitalized for extended stay and rarely discharged from ICU before ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Extraordinary Dispersion Engineering In Enabling Ultrafast Swept Source visiblelight Optical Coherence Tomography
SBC: OPTICENT, INC. Topic: NEIProject Summary This SBIR Phase 1 project focuses on developing, characterizing, and validating a new swept-source laser system to enable the next-generation clinical visible-light optical coherence tomography (vis-OCT). We will develop a novel design of photonic bandgap fiber that comprises Fiber Bragg Grating array to temporally disperse broadband picosecond-pulses to create a wavelength sweepin ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health