Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Clonal Hematopoietic Progenitor Cell Assay

    SBC: Aastrom Biosciences, Inc.            Topic: N/A

    Hematopoiesis, the regulated production of mature blood cells, is a complex scheme of multilineage differentiation which occurs mainly in the bone marrow of adult mammals. Mature cells are continuously produced from progenitor (or precursor) cells. Consequently, assays which detect these progenitor cells are vital in many research and clinical settings. The current assay procedures suffer from a n ...

    SBIR Phase I 1993 Department of Health and Human Services
  2. Hematopoietic Cell Expansion System

    SBC: Aastrom Biosciences, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1993 Department of Health and Human Services
  3. Spatially Modulated Radiographic Illuminator

    SBC: Advanced Technologies/Laboratories Intl            Topic: N/A

    The objective of this project is to develop a system for the optimized viewing of medical x-ray film. Illuminators currently used to view radiographs have a fixed-area, spatially uniform light output. This allows extraneous light to degrade visual performance and limits the viewable film density range to the dynamic range of the eye at a given adaptation level. The proposed viewing system will pro ...

    SBIR Phase I 1993 Department of Health and Human Services
  4. Breast Cancer Quality Assessment Expert System

    SBC: Applied Knowledge Institute,            Topic: N/A

    The goal is to develop a knowledge-based expert management system to deliver cost-effective quality medical care. This system will allow health care providers to plan and allocate services within the existing budgeting and economic constraints. The methodology consists of 1) building an integrated database of clinical and management information, 2) designing the knowledge representation used in th ...

    SBIR Phase I 1993 Department of Health and Human Services
  5. Measurement of Boron Stable Isotopes for Cancer Therapy

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    Development of novel boronated compounds and use of epithermal neutrons has now generated much interest in 10B-boron capture neutron therapy of different tumors. However, no suitable methods exist that allow investigation of their pharmacokinetics in human subjects or in vivo measurement of the ratio of intracellu- lar/extracellular 10B at the time of irradiation. A new approach based on the use o ...

    SBIR Phase I 1993 Department of Health and Human Services
  6. Triple Helix-Based Acoustic Plate Mode DNA Biosensor

    SBC: BIODE, INC.            Topic: N/A

    BIODE will utilize the results of its Phase I research to develop (Phase II) and commercialize (Phase III) a totally new solid state biosensor technology for biological measurements. This technology is based upon the merging of two technologies: Triple Helix Nucleic Acid Probes with Acoustic Plate Mode (APM) micro sensors. Recent advances by BIODE in the design and operation of APM devices have re ...

    SBIR Phase I 1993 Department of Health and Human Services
  7. Moldable MRI Coil for Breast Imaging

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    We will develop a new construction method for receiver coils for magnetic resonance imaging (MRI) of the human breast. These coils will be custom-shaped to individual patients in a quick, economical, and comfortable manner. Since each structure fits the individual patient closely, the coil system permits quantitatively repeatable imaging with accurately reproducible geometry. The structure for sur ...

    SBIR Phase I 1993 Department of Health and Human Services
  8. Measurement of Cochlear Morphology and Physiology

    SBC: Cosmic            Topic: N/A

    The objective is to develop a practical method for measurement of cochlear morphometric and physiological responses from fluorescent microscope images of cochlear tissue. Fluorescent molecular probes are chosen for the particular purpose of the experiments, i. e., marking the location and distribution of actin structural proteins in the organ of Corti. The method quantifies the spatial three dimen ...

    SBIR Phase I 1993 Department of Health and Human Services
  9. Interactive Physiology Simulator for Teaching Medicine

    SBC: Critical Concepts, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1993 Department of Health and Human Services
  10. A PRLIMINARY STUDY OF HANDHELD DATA COLLECTION SYSTEMS FOR HOME HEALTH CARE QUALITY MANAGEMENT

    SBC: Dolley, Keniston & Webb            Topic: N/A

    N/A

    SBIR Phase I 1993 Department of Health and Human Services
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