Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Development of a Reliable, Low-Cost and User-Friendly Spot Test Kit for Leaded Paint and Dust Based on Recent Advances in Bionanotechnology

    SBC: ANDALYZE, INC.            Topic: 05NCERD9

    Lead in household paint and dust is a serious health hazard, as low-level lead exposure can result in a number of adverse health effects, especially in children. Onsite and real-time detection and quantification of lead in paint/dust are very important to homeowners and certified lead-based paint removal professionals. Toward this end, both field-portable equipment (such as X-ray fluorescenc ...

    SBIR Phase I 2006 Environmental Protection Agency
  2. Web-Based Program for Symptom Management in Fibromyalgia

    SBC: Collinge And Associates, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Fibromyalgia (FM) is a complex chronic illness with no known medical cure. Its management depends heavily on the patient's daily efforts in lifestyle, behavior and self-care. Self-monitoring is key to effective self-management but is especially challenging in FM due to the impact of fatigue and cognitive symptoms. Based on a cognitive-behavioral approach, this ...

    SBIR Phase I 2006 Department of Health and Human Services
  3. Software to Facilitate DNA Cloning

    SBC: GSL BIOTECH, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): DNA cloning, also known as gene splicing or recombinant DNA technology, is crucial for all aspects of biomedical and biotechnology research. For example, DNA cloning has been of central importance for sequencing the human genome, generating safer vaccines, identifying genes involved in cancer and many other diseases, and producing therapeutic drugs such as insu ...

    SBIR Phase I 2006 Department of Health and Human Services
  4. Treatment of Calcium Nephrolithiasis Sodium Thiosulfate

    SBC: LITHOLINK CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The broad objective of this proposed research is to determine the effect of sodium thiosulfate on kidney stone formation. The drug will initially be studied in a rat model of nephrolithiasis and if the drug is shown to reduce risk of new stone formation we will study the drug in patients with nephrolithiasis. The long term goal is to bring a new therapy for kid ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. Improvement of RNAi efficacy by blocking RNAi inhibitors

    SBC: SILENTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): RNA Interference (RNAi) promises to become a powerful approach to rational drug design. One significant drawback to RNAi is that its effect on gene expression is rarely 100% potent. This limitation, observed widely, is problematic when a complete cessation of gene expression is desired or required. A major goal of this proposal is to develop targeted strategies ...

    STTR Phase I 2006 Department of Health and Human Services
  6. Technology to access medication label information for severely visually impaired

    SBC: SIXTYSEVEN KILOHERTZ, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop technology that uses the camera function of a cellular phone to read a special graphical code on the label of a prescription medication container. This code would trigger the retrieval of label information, saved on a remote server, which after being run through a text-to-speech engine, would be read aloud to the user through the phone. We ...

    SBIR Phase I 2006 Department of Health and Human Services
  7. Hair Ethyl Glucuronide as a Long Term Alcohol Biomarker

    SBC: United States Drug Testing Laboratories, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a need for a highly sensitive (> 90%) and specific (> 90%) long term biomarker to both detect and monitor individuals who are heavy users of alcohol. Monitoring short term (3-5 days) alcohol use and abuse by impaired professionals by using urine ethyl glucuronide (EtG) has been shown to be both sensitive and specific (> 90%). Recently evidence has emer ...

    SBIR Phase I 2006 Department of Health and Human Services
  8. Activated Sugars for Drug Discovery

    SBC: ZUCHEM INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Natural product glycosylation is vital for the discovery of new pharmaceutical compounds. While it has been recognized for some time that many biologically active natural products owe much of their therapeutic properties to their glycosylation diversity, methods for creating further diversity for drug discovery have been difficult to develop. One of the challen ...

    SBIR Phase I 2006 Department of Health and Human Services
  9. Synthesis and Testing of Neoglycoside Glycopeptide Prototypes

    SBC: ZUCHEM INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I proposal is to develop glycopeptide neoglycosides against VanA-resistant and VanB-resistant organisms. The clinical relevance of such compounds stems from the sharp rise in VRE (vancomycin-resistant enterococci, and more recently staphylococci) infections from below 0.5% in 1989 to >30% in 2000 in U.S. alone. This rise in vancomycin-resistant organ ...

    SBIR Phase I 2006 Department of Health and Human Services
  10. Improvement of RNAi efficacy by blocking RNAi inhibitors

    SBC: SILENTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): RNA Interference (RNAi) promises to become a powerful approach to rational drug design. One significant drawback to RNAi is that its effect on gene expression is rarely 100% potent. This limitation, observed widely, is problematic when a complete cessation of gene expression is desired or required. A major goal of this proposal is to develop targeted strategies ...

    SBIR Phase I 2006 Department of Health and Human Services
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