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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Activated Sugars for Drug Discovery
SBC: ZUCHEM INC. Topic: N/ADESCRIPTION (provided by applicant): Natural product glycosylation is vital for the discovery of new pharmaceutical compounds. While it has been recognized for some time that many biologically active natural products owe much of their therapeutic properties to their glycosylation diversity, methods for creating further diversity for drug discovery have been difficult to develop. One of the challen ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Behavioral Economic MANET for the Treatment of ADHD
SBC: MediaBalance, Inc. Topic: N/ADESCRIPTION (provided by applicant): Attention deficit hyperactivity disorder (ADHD) is the most commonly diagnosed psychiatric disorder in children. Psychostimulant medication and behavioral therapy -- both alone and in combination -- are the primary evidence-based treatments for the functional deficits associated with ADHD. Intensive behavior therapy can reduce the need to use medication. Unfort ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Behavioral economic MANET shape weight loss/maintenance
SBC: MediaBalance, Inc. Topic: N/ADESCRIPTION (provided by applicant): Intensive behavioral interventions are needed to stem the obesity epidemic. Unfortunately, effective implementation of behavioral therapies is limited by the lack of an accurate system for measuring behavior and delivering immediate reinforcement. This SBIR Phase I proposal focuses on testing the feasibility of an innovative wireless platform for shaping key w ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Bile acid conjugates to improve the oral bioavailability of anti-influenza drugs
SBC: TSRL, INC. Topic: N/ADESCRIPTION (provided by applicant): With the concern for an avian influenza pandemic increasing, there is a need to develop antiviral therapies with improved bioavailability. We are developing an enhanced oral delivery platform for anionic small molecule antiviral drugs using zanamivir as our investigational drug. While zanamivir has proven to be a potent and effective inhibitor of influenza neur ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Biodegradable Targeted Nanoparticle for Delivery of Radiosensitizer to Rat Glioma
SBC: MOLECULAR THERAPEUTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): Although surgery and radiation are typically used in the treatment of malignant gliomas, the prognosis and 5-year survival rate for these patents is very poor. Gliomas are typically radioresistant and represent one of the most difficult tumors to treat by noninvasive methods. Gemcitabine is a potent radiosensitizer whose clinical utility is limited by its inher ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Cancer Cluster Morphology
SBC: BIO-ANALYTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): This SBIR Phase I project will develop methods, software and instructional materials for the accurate detection and description of cancer clusters and hotspots. Present state-of-the-art often relies on methods that were defined over a decade ago, do not accurately describe cluster morphology (e.g. shape, excess risk, and boundaries) and that are known to miscla ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Carboxylated polysaccharides for drug delivery to the eye
SBC: BIOPOLYMER INNOVATIONS, LLC Topic: N/ADESCRIPTION (provided by applicant): Many Americans suffer from ocular diseases which require application of topical therapeutic agents. These diseases range from bacterial conjunctivitis to intraocular inflammation. Keratoconjunctivitis sicca (dry eye) affects nearly 30 million people. Glaucoma affects 2 to 3 million Americans. Topical treatments exist but their ability to deliver drugs to the ey ...
STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Carboxylated polysaccharides for drug delivery to the eye
SBC: BIOPOLYMER INNOVATIONS, LLC Topic: N/ADESCRIPTION (provided by applicant): Many Americans suffer from ocular diseases which require application of topical therapeutic agents. These diseases range from bacterial conjunctivitis to intraocular inflammation. Keratoconjunctivitis sicca (dry eye) affects nearly 30 million people. Glaucoma affects 2 to 3 million Americans. Topical treatments exist but their ability to deliver drugs to the ey ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Cell Therapy for Septic Shock
SBC: Innovative Biotherapies, Inc. Topic: N/ADESCRIPTION (provided by applicant): Tissue engineering and cell therapy are a new and exciting approach to the treatment of acute and chronic diseases. The potential success of this therapeutic approach lies in the growing appreciation that most disease processes are not due to the lack of a single protein but develop due to alterations in complex interactions of a variety of cell products. Cell ...
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
COMBINED TARGETED DENDRIMER DIAGNOSTIC-THERAPEUTIC
SBC: DENDRITIC NANOTECHNOLOGIES, INC. Topic: N/AN/A
SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health