Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Improved Rapid Detection of Viable Waterborne Pathogens

    SBC: INNOVATIVE BIOTECHNOLOGIES INTERNATIONAL            Topic: 05NCERA2

    Innovative Biotechnologies International, Inc., has reported previously a simple method to detect viable Cryptosporidium parvum oocysts in drinking water using the isothermic Nucleic Acid Sequence-Based Amplification (NASBA) method, coupled with a rapid liposome nanovesicle (Nanozome)-based biosensor technology.  This assay system is based on the ability to immunocapture low nu ...

    SBIR Phase I 2006 Environmental Protection Agency
  2. Field Analytical Model for Perchlorate

    SBC: IA, Inc.            Topic: 05NCERD4

    Perchlorate is a widely used component of solid fuel, missile and rocket propellants, explosives, and pyrotechnics. It has been shown to reduce iodide uptake into the thyroid gland. The U.S. Environmental Protection Agency (EPA) has found perchlorate contamination in 18 states and believes contamination may exist in as many as 39 states. In early January 2005, the National Academy of Science ...

    SBIR Phase I 2006 Environmental Protection Agency
  3. Development of a Reliable, Low-Cost and User-Friendly Spot Test Kit for Leaded Paint and Dust Based on Recent Advances in Bionanotechnology

    SBC: ANDALYZE, INC.            Topic: 05NCERD9

    Lead in household paint and dust is a serious health hazard, as low-level lead exposure can result in a number of adverse health effects, especially in children. Onsite and real-time detection and quantification of lead in paint/dust are very important to homeowners and certified lead-based paint removal professionals. Toward this end, both field-portable equipment (such as X-ray fluorescenc ...

    SBIR Phase I 2006 Environmental Protection Agency
  4. NOVEL MINIMALLY INVASIVE METHOD TO IDENTIFY LUNG MALIGNANCIES BY MRI

    SBC: 3TP IMAGING SCIENCES            Topic: N/A

    DESCRIPTION (provided by applicant): Project Summary. The overall goal of this research program is to develop a novel magnetic resonance (MR) image analysis method that can distinguish between malignant and benign lung nodules in patients who are undergoing diagnostic evaluation for lung cancer. 3TP Imaging Sciences has developed MR image analysis software that can be used to characterize the stat ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. Transdermal GnRH Delivery System to Treat Infertility

    SBC: ADVANCED SENSOR TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ability to conceive and maintain a pregnancy is a desire most couples expect to fulfill in their lifetime. However, infertility affects between eight and fifteen percent of the American population. One of the most common causes of female infertility is anovulation, or the inability to stimulate and release an egg from the ovary. Although there are a number ...

    SBIR Phase I 2006 Department of Health and Human Services
  6. SHG for Integrin receptor drug discovery

    SBC: Biodesy LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Integrin receptors are critical cell surface proteins involved in cell adhesion and are important in tumor progression. Inhibitors of integrin receptors can be effective anti-cancer agents because they can prevent tumor adhesion and abolish integrin functions which are important for cancer survival and metastasis. The receptors are composed of two subunits, alp ...

    SBIR Phase I 2006 Department of Health and Human Services
  7. Low-cost custom microarray synthesis

    SBC: BIODISCOVERY LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In this project our goal is to develop and commercialize a very low cost microarray chip fabrication technology to reduce the cost by as much as a factor of ten and enable the use of microarrays by groups who can not afford the current generation of microarrays. Our technology combines the standard acid labile DMT protection group containing nucleophosphoramidi ...

    STTR Phase I 2006 Department of Health and Human Services
  8. Cancer Cluster Morphology

    SBC: BIO-ANALYTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This SBIR Phase I project will develop methods, software and instructional materials for the accurate detection and description of cancer clusters and hotspots. Present state-of-the-art often relies on methods that were defined over a decade ago, do not accurately describe cluster morphology (e.g. shape, excess risk, and boundaries) and that are known to miscla ...

    SBIR Phase I 2006 Department of Health and Human Services
  9. Carboxylated polysaccharides for drug delivery to the eye

    SBC: BIOPOLYMER INNOVATIONS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Many Americans suffer from ocular diseases which require application of topical therapeutic agents. These diseases range from bacterial conjunctivitis to intraocular inflammation. Keratoconjunctivitis sicca (dry eye) affects nearly 30 million people. Glaucoma affects 2 to 3 million Americans. Topical treatments exist but their ability to deliver drugs to the ey ...

    STTR Phase I 2006 Department of Health and Human Services
  10. THE YAKK (A new communication device for nonverbal children)

    SBC: BLINK TWICE, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Augmentative and Alternative Communications (AAC) devices are small touchscreen computers which allow nonverbal persons to "speak." The most well-known device is the one used by astrophysicist Stephen Hawking. However, generating language with AAC devices is cumbersome and mechanical, particularly for children. As such, communication is never optimal and is rar ...

    SBIR Phase I 2006 Department of Health and Human Services
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