Award Data

Innovative Biotechnologies International, Inc., has reported previously a simple method to detect viable Cryptosporidium parvum oocysts in drinking water using the isothermic Nucleic Acid Sequence-Based Amplification (NASBA) method, coupled with a rapid liposome nanovesicle (Nanozome)-based biosensor technology. This assay system is based on the ability to immunocapture low numbers ...

Perchlorate is a widely used component of solid fuel, missile and rocket propellants, explosives, and pyrotechnics. It has been shown to reduce iodide uptake into the thyroid gland. The U.S. Environmental Protection Agency (EPA) has found perchlorate contamination in 18 states and believes contamination may exist in as many as 39 states. In early January 2005, the National Academy of Science ...

Lead in household paint and dust is a serious health hazard, as low-level lead exposure can result in a number of adverse health effects, especially in children. Onsite and real-time detection and quantification of lead in paint/dust are very important to homeowners and certified lead-based paint removal professionals. Toward this end, both field-portable equipment (such as X-ray fluorescenc ...

A radio frequency (RF) photoemission source that delivers polarized electrons at low emittance would be an attractive electron source for a linear collider. Moreover, it has been demonstrated recently that such a source, in conjunction with nearby injection-system optics, can deliver a beam with a high ratio of transverse emittances, leading to a simplification or elimination of a linear collider ...

DESCRIPTION (provided by applicant): Project Summary. The overall goal of this research program is to develop a novel magnetic resonance (MR) image analysis method that can distinguish between malignant and benign lung nodules in patients who are undergoing diagnostic evaluation for lung cancer. 3TP Imaging Sciences has developed MR image analysis software that can be used to characterize the stat ...

DESCRIPTION (provided by applicant): The ability to conceive and maintain a pregnancy is a desire most couples expect to fulfill in their lifetime. However, infertility affects between eight and fifteen percent of the American population. One of the most common causes of female infertility is anovulation, or the inability to stimulate and release an egg from the ovary. Although there are a number ...

Second generation, coated superconductor wires (YBCO material), needed for electricity transmission, have demonstrated the ability to produce 100 Amp, long-length conductors at approximately 10 times the cost of copper wires. This cost is unacceptable. In order to meet the DOE¿s cost target of $10/kA-m, significant improvements in current-carrying-density capability will be required, with a tar ...

DESCRIPTION (provided by applicant): It is estimated that the annual incidence of spinal cord injury (SCI), not including those who die at the scene of the accident, is approximately 11,000 cases each year. The number of living patients in the United States as of December 2003 who have SCI, has been estimated as being approximately 243,000 persons. After initial injury, about half of those affect ...

DESCRIPTION (provided by applicant): The confocal fluorescent microscope directly eliminates the light emitted from out-of-focus internal structures. This has enabled the observation of fluorophore-labeled processes or 3D structures deep within thick specimens. Unfortunately, high performance objective lenses are designed for immersion fluids, such as oil, glycerol, or water; the index of the spec ...

DESCRIPTION (provided by applicant): Integrin receptors are critical cell surface proteins involved in cell adhesion and are important in tumor progression. Inhibitors of integrin receptors can be effective anti-cancer agents because they can prevent tumor adhesion and abolish integrin functions which are important for cancer survival and metastasis. The receptors are composed of two subunits, alp ...