Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Development of a Reliable, Low-Cost and User-Friendly Spot Test Kit for Leaded Paint and Dust Based on Recent Advances in Bionanotechnology

    SBC: ANDALYZE, INC.            Topic: 05NCERD9

    Lead in household paint and dust is a serious health hazard, as low-level lead exposure can result in a number of adverse health effects, especially in children. Onsite and real-time detection and quantification of lead in paint/dust are very important to homeowners and certified lead-based paint removal professionals. Toward this end, both field-portable equipment (such as X-ray fluorescenc ...

    SBIR Phase I 2006 Environmental Protection Agency
  2. A TEQ Based Dioxin Kit Utilizing Fluorescent Aptamers

    SBC: Eno River Labs, LLC            Topic: 05NCERC3

    Eno River Labs, LLC, (ERL) proposes to develop an onsite testing kit for dioxins that uses fluorescently tagged ssDNA aptamers for selective binding and subsequent screening and quantitative analysis of dioxin in soil sample.  Current dioxin field test kits are immunoassay based, which are insufficiently specific and sometimes unreliable.  Reliable dioxin testing requires la ...

    SBIR Phase I 2006 Environmental Protection Agency
  3. Field Analytical Model for Perchlorate

    SBC: IA, Inc.            Topic: 05NCERD4

    Perchlorate is a widely used component of solid fuel, missile and rocket propellants, explosives, and pyrotechnics. It has been shown to reduce iodide uptake into the thyroid gland. The U.S. Environmental Protection Agency (EPA) has found perchlorate contamination in 18 states and believes contamination may exist in as many as 39 states. In early January 2005, the National Academy of Science ...

    SBIR Phase I 2006 Environmental Protection Agency
  4. Nanoliter Lab-on-a-Chip for Rapid Parallel Immunoassays

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The development of clinically effective cancer vaccines requires reliable analytical methods to evaluate the immune response to vaccination. Immunoassays are among the most sensitive and specific analytical methods that have been used widely in cancer vaccine research, most commonly to monitor the release of cytokines from T-cells in response to vaccination. A ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. Transdermal GnRH Delivery System to Treat Infertility

    SBC: ADVANCED SENSOR TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ability to conceive and maintain a pregnancy is a desire most couples expect to fulfill in their lifetime. However, infertility affects between eight and fifteen percent of the American population. One of the most common causes of female infertility is anovulation, or the inability to stimulate and release an egg from the ovary. Although there are a number ...

    SBIR Phase I 2006 Department of Health and Human Services
  6. Discovery of a Platelet Derived Growth Factor Peptide-based Mimetic

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Summary/Abstract Diabetic foot ulcers are a significant health problem that imposes high costs on both patients and society (Boulton, Vileikyte et al. 2005). A large proportion of foot ulcers remain unresponsive to available conventional treatment and their associated complications and costs have prompted extensive research that has led to promising breakthroug ...

    SBIR Phase I 2006 Department of Health and Human Services
  7. Click Chemistry for Immobilized Bone Morphogenetic Protein

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): There are over 6.3 million fractures each year in the United States of which approximately 700,000 are difficult to heal. The available treatment options for fractures that do not heal or are slow to heal are limited. Bone morphogenetic proteins are growth factors that stimulate new bone production and have received FDA approval for bone fracture repair and spi ...

    SBIR Phase I 2006 Department of Health and Human Services
  8. Injectable BMP-2 Formulation for Fracture Healing

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Two recombinant human Bone Morphogenetic Proteins (BMP's), rhBMP-2 and rhBMP-7, are currently used in clinical applications to promote spinal fusion and fracture healing (Mont, Ragland et al. 2004). Over 6.3 million fractures occur each year in the United States alone (Praemer, Furner et al. 1999). Approximately 15% of fractures have delayed or impaired healing ...

    SBIR Phase I 2006 Department of Health and Human Services
  9. Growth Factor Coated Sutures for Improved Tendons Repair

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Tendon injuries are quite common and the frequency of these injuries is expected to rise as the population ages, yet continues to remain active. Long periods of immobilization and rehabilitation are required because tendon healing is a relatively slow process. Innovations that can shorten this time period by improving healing rates and increasing the strength o ...

    SBIR Phase I 2006 Department of Health and Human Services
  10. Low-cost custom microarray synthesis

    SBC: BIODISCOVERY LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In this project our goal is to develop and commercialize a very low cost microarray chip fabrication technology to reduce the cost by as much as a factor of ten and enable the use of microarrays by groups who can not afford the current generation of microarrays. Our technology combines the standard acid labile DMT protection group containing nucleophosphoramidi ...

    STTR Phase I 2006 Department of Health and Human Services
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