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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Pharmacological Validation of GIV/Girdin, a Guanine Nucleotide Exchange Factor, for Liver Fibrosis

    SBC: Bellbrook Labs, LLC            Topic: N

    Project Summary The broad goal of this project is the pharmacological validation of GIV a nonreceptor guanine nucleotide exchange factor GEF for liver fibrosis GIV sits at the hub of profibrogenic signaling in liver fibrosis and is required for the key physiological events that lead to this condition the migration proliferation and extracellular matrix deposition of hepatic stellate cells ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a rapid and inexpensive luciferase-based high throughput screening assay to identify compounds that alter pancreatic β cell function

    SBC: Regenerative Medical Solutions Inc            Topic: 200

    Project Summary Abstract The prevalence of diabetes in the United States and world wide is increasing dramatically and new drugs that can protect or restore the function of insulin producing pancreatic beta cells are urgently needed For decades diabetes drug discovery efforts have been hampered by two things the lack of abundant human beta cells for drug screening and the difficultly an ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Engineered pancreatic endocrine cells that report beta cell toxicity for use in high throughput screening applications

    SBC: Regenerative Medical Solutions Inc            Topic: 200

    Project Summary Abstract The prevalence of diabetes in the United States and world wide is increasing dramatically and new drugs that can protect or restore the function of insulin producing pancreatic beta cells are urgently needed For decades drug discovery efforts in this space have been hampered by the lack of consistent and abundant human beta cells for drug screening The advent of beta c ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A mobile app to reduce treatment-related financial burden for cancer patients

    SBC: Vivor, Llc            Topic: NCI

    There is a fundamental knowledge gap in how to immediately reduce cancer patientsandapos treatment related financial burden Cancer patients pay more out of pocket for their care than those with other chronic illnesses Half of all elderly cancer patients have high treatment related out of pocket financial burden This financial burden has well defined harmful effects even among insured cancer pa ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Cardiac Ventricular Assist Catheter

    SBC: MICHIGAN CRITICAL CARE CONSULTANTS, INC.            Topic: NICHD

    ABSTRACT Extracorporeal membrane oxygenation ECMO use continues to increase as a supportive measure for cardio respiratory failure Pediatric patients with severe acute left ventricular LV systolic dysfunction are often supported with venoarterial VA ECMO as a short term bridge to recovery transplant or a ventricular assist device VAD Although this often provides the much needed tempora ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. An Ultra filtrate perfusion bio artificial pancreas for high-density islet replacement without immunosuppression

    SBC: Norfolk Medical Products, INC.            Topic: NIDDK

    DESCRIPTION provided by applicant The Cell SafeTM is a fundamentally new approach in replacement of dysfunctional insulin producing cells in patients with diabetes by transplantation of new islets in a three dimensional scaffold embedded in a highly compatible bioengineered perfusion system that continuously supplies tissue fluid blood ultrafiltrate so that the cells ae protected from immun ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Real-time volumetric specimen imager for 3D intra-operative lumpectomy margin assessment

    SBC: CLARIX IMAGING CORP            Topic: 102

    DESCRIPTION provided by applicant We propose to develop a novel volumetric specimen imager VSI device for significantly reducing breast lumpectomyandapos s reoperation rate and improving outcomes Among the annual performance of andgt lumpectomies in the US up to of patients need a reoperation when post surgery pathology examination reveals andquot positive marginandquot ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Furopyrroles as Novel anti-Ebola Agents

    SBC: Chicago Biosolutions, Inc.            Topic: NCZVBED

    DESCRIPTION provided by applicant Ebola EBOV and Marburg MARV viruses belong to the family Filoviridae and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction with an incubation period of days Because of the safety concerns these viruses are designated as the biosafety level agents Currently there is no effective vaccine or therapeutic treatment again ...

    SBIR Phase I 2016 Department of Health and Human ServicesCenters for Disease Control and Prevention
  9. C i Supplement Development of an Active Spinal Orthosis for the Treatment of Vertebral Compression and Burst Fractures

    SBC: EXO DYNAMICS LLC            Topic: NIBIB

    Significance of Research Exo Dynamics seeks to develop a novel active spinal orthosis that will enhance the outcomes of bracing treatment for the most common osteoporotic spinal fractures The goal is to create a device that will enhance outcomes through monitored use and provide consistent continuous support through a complete range of motion ROM This device may reduce pain enhance mobilit ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Manufacturing Design of Bio-based Ceiling Tiles using Nanocellulose

    SBC: REVOLUTION RESEARCH, INC.            Topic: 15NCER06

    Suspended ceiling tiles are widely used in commercial and residential construction because they offer flexibility and easy access to utilities. Most of the available tiles absorb water, resulting in sagging, staining, and mold/mildew growth. They also contain potentially hazardous chemicals and release airborne fibers when broken or cut. Existing tiles are not durable, requiring frequent replaceme ...

    SBIR Phase I 2016 Environmental Protection Agency
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