Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Development of a Reliable, Low-Cost and User-Friendly Spot Test Kit for Leaded Paint and Dust Based on Recent Advances in Bionanotechnology

    SBC: ANDALYZE, INC.            Topic: 05NCERD9

    Lead in household paint and dust is a serious health hazard, as low-level lead exposure can result in a number of adverse health effects, especially in children. Onsite and real-time detection and quantification of lead in paint/dust are very important to homeowners and certified lead-based paint removal professionals. Toward this end, both field-portable equipment (such as X-ray fluorescenc ...

    SBIR Phase I 2006 Environmental Protection Agency
  2. Novel Feedstock for Biodegradable Plastic

    SBC: Montana Biotech SE, Inc.            Topic: 05NCERD1

    Landfills and waterways are inundated with tons of nondegradable plastics derived from petrochemicals. An unusual polysaccharide has been identified that can be extruded as a biodegradable plastic. Unique properties allow it to replace certain petroleum-based plastics at the same price as other bioplastics. To gain quick acceptance, details of the process developed during the Phase I project will ...

    SBIR Phase I 2006 Environmental Protection Agency
  3. Development of Neurotensin-based Analgesics

    SBC: ARGOLYN BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic, neuropathic pain is one of the most important unmet medical needs in the United States, affecting tens to hundreds of millions of people nationwide at some time during their lives. Novel therapeutic approaches are desperately needed. The brain peptides neurotensin (NT) and its fully active derivative NT[8- 13] have been shown to exhibit considerable, l ...

    SBIR Phase I 2006 Department of Health and Human Services
  4. PRESERVATION OF LIVER SPHEROIDS

    SBC: Cell & Tissue Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Assays are being developed in efforts to reduce the number of animals required for research. In particular, cell based systems that can evaluate a variety of compounds and/or screen single compounds with many cell types would provide the most advantageous platforms. These types of assay systems would be applicable to drug discovery, toxicology testing and envir ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. New Solutions Islet Recovery Preservation of Pancreas

    SBC: Cell & Tissue Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Transplantation of islets of Langerhans for the clinical treatment of Type I diabetes has had a resurgence of interest due to results obtained using the "Edmonton protocol". However, at this time, procurement of donor pancreases for islet isolation and transplantation is in its infancy. Most pancreases at more remote donor sites are not procured due to justifie ...

    SBIR Phase I 2006 Department of Health and Human Services
  6. Freeze-Dried, Viable Allogeneic Heart Valves

    SBC: Cell & Tissue Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Allogeneic human heart valves are used in approximately 20% of the tissue heart valve procedures performed annually. Most allogeneic human heart valves (also known as allografts or homografts) are cryopreserved and stored in the vapor phase of liquid nitrogen storage freezers. During shipping from the preservation facility to the surgical point of use, the hear ...

    SBIR Phase I 2006 Department of Health and Human Services
  7. Web-Based Program for Symptom Management in Fibromyalgia

    SBC: Collinge And Associates, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Fibromyalgia (FM) is a complex chronic illness with no known medical cure. Its management depends heavily on the patient's daily efforts in lifestyle, behavior and self-care. Self-monitoring is key to effective self-management but is especially challenging in FM due to the impact of fatigue and cognitive symptoms. Based on a cognitive-behavioral approach, this ...

    SBIR Phase I 2006 Department of Health and Human Services
  8. A High-Performance Quiet Gradient Coil for High-field Whole-body MRI

    SBC: DOTY SCIENTIFIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Preliminary data demonstrate that a radically different approach to MRI gradient coil design permits substantial advantages in all respects; especially in short, high-field magnets - higher gradient strength, reduced acoustic noise, and reduced nerve stimulation. A major advance in whole-body MRI gradient coil technology would be of fundamental benefit to the f ...

    SBIR Phase I 2006 Department of Health and Human Services
  9. Restoration of Skin Structure and Function Post-Wounding

    SBC: FirstString Research, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The wound repair process in skin is initiated immediately after an injury and induces a cascade of events including inflammation, proliferation, and scar production/tissue remodeling. One of the common complications of wound healing is excessive scarring, leading to undesirable changes in skin mechanical function, as well as cosmetic disfiguration. The adverse ...

    STTR Phase I 2006 Department of Health and Human Services
  10. Software to Facilitate DNA Cloning

    SBC: GSL BIOTECH, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): DNA cloning, also known as gene splicing or recombinant DNA technology, is crucial for all aspects of biomedical and biotechnology research. For example, DNA cloning has been of central importance for sequencing the human genome, generating safer vaccines, identifying genes involved in cancer and many other diseases, and producing therapeutic drugs such as insu ...

    SBIR Phase I 2006 Department of Health and Human Services
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