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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development of a Reliable, Low-Cost and User-Friendly Spot Test Kit for Leaded Dust Based on Recent Advances in Bionanotechnology

    SBC: ANDALYZE, INC.            Topic: 06NCERP1

    Lead in household paint and dust is a serious health hazard, as low-level lead exposure can result in a number of adverse health effects, especially in children. Onsite and real-time detection and quantification of lead in paint/dust are very important to homeowners and certified lead-based paint removal professionals. Toward this end, both field-portable equipment (such as X-ray fluorescence inst ...

    SBIR Phase II 2007 Environmental Protection Agency
  2. Investigation of Solvent Toxicity in Bacterial Strains Involved in Butanol Production

    SBC: Integrated Genomics, Inc.            Topic: 06NCERD1

    Reduction in dependency on imported petroleum and the quest to identify renewable energy sources has led to a search for innovative biofuels derived from renewable biomass, which promise long-term reductions in greenhouse gas emissions. Butanol is one possible biofuel. It is an industrial fuel that can be produced from crops using acetone-butanol (AB) fermentation by butanolagenic microbes, such a ...

    SBIR Phase I 2007 Environmental Protection Agency
  3. Novel neutral antagonist for the treatment of opioid-induced adverse effects

    SBC: AIKO BIOTECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): AIKO Biotechnology, Inc. is a start-up biotechnology company focused on developing safe and effective therapeutics for the management of pain and addiction. Opioid drugs are the standard of care in the treatment of pain. However, opioids produce a spectrum of adverse effects, including opioid-induced bowel dysfunction, that limit their clinical utility. Opioid ...

    SBIR Phase I 2007 Department of Health and Human Services
  4. Improving colonoscopic miss rate by real time microvascular blood analysis

    SBC: American BioOptics, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this small business technology transfer application is to validate and commercialize an improved means of polyp detection during colonoscopy: spectroscopic microvascular blood assessment from the endoscopica lly normal mucosa. Missed lesions on colonoscopy are a major problem (conservatively estimated to be ~25% of adenomas and ~4-5% of carcinomas) ...

    STTR Phase I 2007 Department of Health and Human Services
  5. Development of Accurate Test Kits for Malabsorption


    Accurate measurement of gastrointestinal absorption of various substances is important in bothresearch and diagnosis. In many cases, the acceptable general approach is the balance procedure. Thisprocedure suffers from the requirement for complete collection of stools over an extended period oftime. This limitation prevents widespread use of this otherwise desirable approach. The investigatorspropo ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. Micron Resolution Volume-Computed Tomography

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    Instrumentation that can provide microstructural characterization of medical grade polymers,fabrics, and composite materials is the proposed research's long term goal. One micron resolutionvolume computed tomography of test specimens can now be demonstrated by combining anNIST-developed x-ray microscope with BIR's volume CT capability. Micro VCT will be a valuable toolin the development of new med ...

    SBIR Phase I 1994 Department of Health and Human Services
  7. Fiber Optic Sensor for Cardiac Magnetic Field

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    We will adapt a non-cryogenic magnetic field sensor previously developed for defense purposesand apply it to magnetocardiography (MCG), the measurement of magnetic fields induced by electricalcurrents in the heart. As a single non-invasive sensor, this unit would have similar applications to theelectrocardiograph. When these units are assembled into a spatial array, the magnetic field can bemeasur ...

    SBIR Phase I 1994 Department of Health and Human Services

    SBC: BRIGHTOUTCOME INC.            Topic: N/A


    SBIR Phase I 2007 Department of Health and Human Services

    SBC: BRIGHTOUTCOME INC.            Topic: N/A


    SBIR Phase I 2007 Department of Health and Human Services
  10. Novel Compounds for the Treatment of Memory Disorders

    SBC: Chicago Institute For Neuro            Topic: N/A

    We have generated a monoclonal antibody, B6B21, and have shown that it significantlyenhances acquisition rates in hippocampus-dependent trace eyeblink conditioning in rabbits, halving thenumber of trials required to reach 80% conditioned responses. Previous studies, with a variety of modelsystems, have shown that B6B21 acts as a partial ago mst at the glycine site of the N-methyl-D-aspart-ate rece ...

    SBIR Phase I 1994 Department of Health and Human Services

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