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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel neutral antagonist for the treatment of opioid-induced adverse effects

    SBC: AIKO BIOTECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): AIKO Biotechnology, Inc. is a start-up biotechnology company focused on developing safe and effective therapeutics for the management of pain and addiction. Opioid drugs are the standard of care in the treatment of pain. However, opioids produce a spectrum of adverse effects, including opioid-induced bowel dysfunction, that limit their clinical utility. Opioid ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  2. Improving colonoscopic miss rate by real time microvascular blood analysis

    SBC: American BioOptics, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this small business technology transfer application is to validate and commercialize an improved means of polyp detection during colonoscopy: spectroscopic microvascular blood assessment from the endoscopica lly normal mucosa. Missed lesions on colonoscopy are a major problem (conservatively estimated to be ~25% of adenomas and ~4-5% of carcinomas) ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Accurate Test Kits for Malabsorption

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    Accurate measurement of gastrointestinal absorption of various substances is important in bothresearch and diagnosis. In many cases, the acceptable general approach is the balance procedure. Thisprocedure suffers from the requirement for complete collection of stools over an extended period oftime. This limitation prevents widespread use of this otherwise desirable approach. The investigatorspropo ...

    SBIR Phase I 1994 Department of Health and Human Services
  4. Micron Resolution Volume-Computed Tomography

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    Instrumentation that can provide microstructural characterization of medical grade polymers,fabrics, and composite materials is the proposed research's long term goal. One micron resolutionvolume computed tomography of test specimens can now be demonstrated by combining anNIST-developed x-ray microscope with BIR's volume CT capability. Micro VCT will be a valuable toolin the development of new med ...

    SBIR Phase I 1994 Department of Health and Human Services
  5. Fiber Optic Sensor for Cardiac Magnetic Field

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    We will adapt a non-cryogenic magnetic field sensor previously developed for defense purposesand apply it to magnetocardiography (MCG), the measurement of magnetic fields induced by electricalcurrents in the heart. As a single non-invasive sensor, this unit would have similar applications to theelectrocardiograph. When these units are assembled into a spatial array, the magnetic field can bemeasur ...

    SBIR Phase I 1994 Department of Health and Human Services
  6. SBIR PHASE I- TOPIC # 235- HOME CENTERED TELEONCOLOGY CARE MODEL

    SBC: BRIGHTOUTCOME INC.            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  7. TITLE: PATIENT-REPORTED OUTCOMES (PRO) MANAGEMENT SYSTEM. SBIR TOPIC 212.

    SBC: BRIGHTOUTCOME INC.            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Compounds for the Treatment of Memory Disorders

    SBC: Chicago Institute For Neuro            Topic: N/A

    We have generated a monoclonal antibody, B6B21, and have shown that it significantlyenhances acquisition rates in hippocampus-dependent trace eyeblink conditioning in rabbits, halving thenumber of trials required to reach 80% conditioned responses. Previous studies, with a variety of modelsystems, have shown that B6B21 acts as a partial ago mst at the glycine site of the N-methyl-D-aspart-ate rece ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. Binaural Assessment Instrument for Cochlear Implants

    SBC: COMPREVAL, INC.            Topic: N/A

    DESCRIPTION (Provided by applicant): The practice of evidence-based medicine requires efficient, easy to use, standardized outcome assessment protocols and instruments with known reliability and validity. At present, there exist no protocols and instruments that are practical for clinical use on a daily basis to assess the benefit of cochlear implants (CIs). The need for such protocols and instrum ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  10. Interactive Physiology Simulator for Teaching Medicine

    SBC: Critical Concepts, Inc.            Topic: N/A

    We will develop a computer simulation of the critically ill patient for use in training medical students, residents, nurses, fellows, and physicians. This computer software will faithfully simulate the functional aspects of cardiopulmonary physiology, using state-of-the-art mathematical models. For the first time, students at all levels will have the freedom to learn medical physiology and therape ...

    SBIR Phase II 1994 Department of Health and Human Services
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