Award Data

DESCRIPTION provided by applicant Over percent of the U S population is currently overweight or obese percent are obese Obesity is a primary cause of numerous chronic diseases including type II diabetes cancer heart disease and the metabolic syndrome Behavioral weight loss interventions have successfully resulted in significant clinical improvements in weight percent weight lo ...

Project Summary! This STTR Phase II project continues the development of the Newborn Acuity Cardstm and the Newborn Contrast Cardstm Together these Newborn Cards form a new clinical test of visual acuity and contrast sensi tivity for use on newborn full term and preterm infants The stimuli are square wave gratings which the examiner presents to the infant in a fixation and following protocol ...

Ebola EBOV and Marburg MARV viruses belong to the family Filoviridae and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction with an incubation period of days Because of the safety concerns these viruses are designated as the biosafety level agents Currently there is no effective vaccine or therapeutic treatment against filoviral infection and pathogenes ...

DESCRIPTION provided by applicant Stroke the leading cause of disability cognitive impairment and death in the US imposes significant financial and personal burden The residual effects of stroke affect many aspects of life not addressed by traditional rehabilitation treatments In particular persons with mild stroke typically defined as a stroke with no or sligh motor impairment and a high ...

Influenza A viruses belong to the orthomyxoviridae family with a negative sense segmented RNA genome which can cause seasonal or pandemic flu with high morbidity and significant mortality Vaccination is the most prevalent prophylactic means for controlling influenza infections However an effective vaccine usually takes at least months to develop for the circulating strains Furthermore vac ...

DESCRIPTION provided by applicant This application is in response to RFA EB a special SBIR program to reduce health disparities by developing medical technologies that are andquot effective affordable culturally acceptable and easily accessible to those who need them andquot It is based on the well established partnership between BrightOutcome and Dr Ana Maria Lopez Associate Vice ...

Proton radiography produces images of patients in terms of proton stopping power by tracking individual protons before and after the patient and measuring the proton residual range after traversing the patient and would be the most direct method of image guidance for proton radiation therapy Radiation therapy is needed for more than of the million Americans who are annually diagnosed wi ...

DESCRIPTION provided by applicant Prostate cancer is the leading cancer among U S men The biggest limitation of current prostate cancer management is that currently it is essentially impossible to accurately prognosticate which patients harbor aggressive cancers that progress into a metastatic disease and need treatment and which patients have non aggressive indolent cancers that would not ...

Project Summary Abstract This goal of this SBIR project is to develop a commercial grade Nanocytology system for FDA clinical trials and subsequent commercialization of a lung cancer risk stratification test to personalize lung cancer screening Lung cancer is the leading cause of cancer deaths in the U S The reason for the lethality of lung cancer relates to its tendency to be diagnosed at a lat ...

PROJECT SUMMARY Neuropathic pain NP conditions affect up to of the population while the annual costs of treatment reach $ billion in the US Pain reduction is more difficult to achieve in NP since the mechanisms involved are not the same as the mechanisms of normal nociceptive pain Current therapeutic approaches offer limited pain relief and frequently produce side effects that outweig ...