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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Colonoscope Force Monitor

    SBC: ARTANN LABORATORIES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Colonoscopy is the preferred method to screen for colorectal cancer, a disease that afflicts 115,000 new patients a year. Several million screening, diagnostic and therapeutic colonoscopies are performed each year in U.S. hospitals and ambulatory surgery centers. However, colonoscopy remains a highly operator dependent activity and no clear definition of skill ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  2. A Topical Non Steroidal Anti-inflammatory for Rosacea

    SBC: SIGNUM BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Rosacea is a chronic dermatological condition characterized by flushing, erythema, papules, pustules, inflammatory nodules and telangiectasia. Although disease etiology remains unclear, skin inflammation has been identified as the main contributor to disease pathology. Isoprenylcysteine (IPC) analogs represent a novel class of topical anti-inflammatory compound ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  3. Development of next-generation Thrombelastographs

    SBC: CORAMED TECHNOLOGIES            Topic: NHLBI

    DESCRIPTION (provided by applicant): Coramed is commercializing next-generation point of care instruments, the TEG 6000 series, for monitoring patient hemostasis on demand. This project includes activities to take the technology from the prototype stage completed in Phase II to FDA-cleared and CLIA-waived commercial products. The planned devices introduce a completely new technology for monitoring ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Pharmacological Treatment for Neuropathic Pain

    SBC: Aptinyx Inc            Topic: 105

    PROJECT SUMMARY Neuropathic pain NP conditions affect up to of the population while the annual costs of treatment reach $ billion in the US Pain reduction is more difficult to achieve in NP since the mechanisms involved are not the same as the mechanisms of normal nociceptive pain Current therapeutic approaches offer limited pain relief and frequently produce side effects that outweig ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Enabling Technology to Prepare Ultrapure Dialysate in Dialysis Clinics

    SBC: NOVAFLUX TECHNOLOGIES, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The clinical significance of chronic pro-inflammatory reactions in dialysis patients due to exposure to endotoxin has become a central issue in nephrology. The European Renal Association urges the routine use of ultrapure dialysate with bacteria and endotoxin levels of lt 0.1 CFU/ml and lt 0.03 EU/ml, respectively. In the US, the maximum allowable limit of ba ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Validation of a rapid point-of-care breath test for breast cancer

    SBC: MENSSANA RESEARCH INC            Topic: NCI

    DESCRIPTIONprovided by applicantThe clinical problemBreast cancer is the commonest cancer in womenin whom it is second only to lung cancer as a cause of cancer deathMammography is the mainstay of screening for breast cancerthough its value is limited by its large number of false positive and false negative findingsA new solution the problemThe combination of two diagnostic tests with different bio ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Colon cancer risk-stratification via optical analysis of rectal ultrastructure

    SBC: American BioOptics, LLC            Topic: NCI

    DESCRIPTIONprovided by applicantThe goal of this small business innovation research grant is to develop and commercialize a highly accurateminimally invasive risk stratification technique for colorectal cancerCRCthat is simple enough to be performed by the primary care provider during an annual physical examAlthough existing guidelines recommend CRC screening for all patients over agertmillion Ame ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Point of Care System for Determination of Bilirubin Capacity in Neonates

    SBC: AVIV BIOMEDICAL INC            Topic: 400

    DESCRIPTION provided by applicant Neonatal hyperbilirubinemia occurs in almost all newborns and may be benign if its progression to extreme hyperbilirubinemia is recognized monitored and prevented or managed in a timely manner Neonatal jaundice carries the risk of neurotoxicity due to the deposition of bilirubin in the central nervous system Most of the bilirubin in plasma is bound to pla ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A Proton Radiography System for Optimization of Proton Therapy

    SBC: ProtonVDA LLC            Topic: 102

    Proton radiography produces images of patients in terms of proton stopping power by tracking individual protons before and after the patient and measuring the proton residual range after traversing the patient and would be the most direct method of image guidance for proton radiation therapy Radiation therapy is needed for more than of the million Americans who are annually diagnosed wi ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Development of protein therapeutic for acute kidney injury

    SBC: TRIM-EDICINE INC            Topic: 400

    Project Summary This direct Phase II SBIR proposal focuses on the development of recombinant human MGrhMGa novel tissue repair proteinas a therapeutic candidate targeting injury of renal epithelium to protect against acute kidney injuryAKIAKI is commonly encountered in the hospital and outpatient settings and is associated with a high rate of mortalityCurrentlythere is no effective means for preve ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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