Award Data

ABSTRACT Sanaria s Plasmodium falciparumPfsporozoiteSPZvaccines development program is receiving global supportTrials of PfSPZ Vaccineradiation attenuated PfSPZor PfSPZ CVacPfSPZ Chemoprophylaxis Vaccineadministered by direct venous inoculationDVIincludingadults to infants were initiated in DecemberTanzaniaU Sor will be initiated in earlyin MaliKenyainfantsGhanaEquatorial GuineaGermany andaddition ...

DESCRIPTIONprovided by applicantThe world needs a highly effective malaria vaccineSanaria rPfSPZ Vaccinecomposed of asepticpurifiedcryopreserved radiation attenuated PfSPZprotectedof volunteers in an NIH clinical trialThe vaccine has been administered by direct venous inoculationDVItosubjects in MaliTanzaniaEquatorial GuineaEGand USASafetytolerabilityhigh grade protectionheterologous protection af ...

DESCRIPTIONprovided by applicantComprehensive bio psychosocial screeningwhich covers not only physical symptoms and psychosocial issuesbut also practical concerns such as transportationfinanceswork and childcareoffers the true opportunity to maximize the benefits of medical care and social support to patients and their families while enhancing operational efficiency and resource management for hea ...

DESCRIPTION provided by applicant Over percent of the U S population is currently overweight or obese percent are obese Obesity is a primary cause of numerous chronic diseases including type II diabetes cancer heart disease and the metabolic syndrome Behavioral weight loss interventions have successfully resulted in significant clinical improvements in weight percent weight lo ...

A NEW HOLOGRAPHIC D CAMERA FOR FUNDUS IMAGING Abstract In the United States retinal disease is the most common cause of visual impairment with age related macular degeneration AMD and diabetic retinopathy DR being the most common retinal diseases For each of the above conditions high resolution and three dimensional D imaging of the retina retinal vasculature choroid and or retinal ...

DESCRIPTION provided by applicant In this Fast Track application a path to commercialization will be pursued for a breakthrough andquot genetic cytologyandquot test capable of detecting both ovarian and endometrial cancer from routinely collected Pap specimens In deference to the notable success of the Pap test in reducing deaths due to cervical cancer and in reference to the core enabling ...

Project Summary Abstract Radiofrequency ablation RFA is a minimally invasive method used to treat solid tumors commonly primary liver cancers and metastases which are accessible percutaneously via a sharp needle Imaging guidance typically by ultrasound or CT is required for probe placement but these methods are incapable of monitoring the progress of the procedure Additional imaging sessi ...

DESCRIPTIONprovided by applicantThe goal of this small business innovation research grant is to develop and commercialize a highly accurateminimally invasive risk stratification technique for colorectal cancerCRCthat is simple enough to be performed by the primary care provider during an annual physical examAlthough existing guidelines recommend CRC screening for all patients over agertmillion Ame ...

PROJECT SUMMARY This Phase II project aims to continue development of a commercial qualityinnovative cloud hosted information management systemcalled Climbthat will increase laboratory efficiency and provide improved capabilities for research laboratoriesClimb is designed to offer integrated laboratory process management modules that include mobile communications tools data monitoring and alert sy ...

Summary The long term objective of the project is to implement new motion robust magnetic resonance imagingMRItechnology into wide clinical and research useMagnetic resonance imaging is a powerful tool that aids in the diagnosis of individual subjectsguides their clinical careand provides insights into the mechanisms of normal and atypical developmentThe characterization of mental health disorders ...