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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nezavist a Novel Molecule for Treatment of Alcohol Use Disorder

    SBC: LOHOCLA RESEARCH CORPORATION            Topic: 150

    Abstract for Supplement ApplicationThe ultimate goal for our original project was to complete the proof-of-concept work, and the multitude of pharmacodynamic, pharmacokinetic, toxicokinetic, safety, and toxicology studies required by the FDA to apply for an IND. We are fully satisfied that we have generated a new chemical entity that acts at a novel binding site on the GABA-A receptor and acts in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Continuous Monitoring of COVID-19 Symptomatology for Elderly Patients in Long Term Care Facilities Using Advanced, Soft, and Flexible Sensors Mounted on the Suprasternal Notch

    SBC: Sonica LLC            Topic: NIA

    PROJECT SUMMARY: COVID-19 is significantly more lethal in the elderly1 with the greatest risk in those cared for in long-term care facilities (LTCs) where mortality rates range from 19% to 72% worldwide. Monitoring COVID-19 infections in LTCs remains a particular challenging. The existing and a continued expected shortage of sufficient molecular COVID-19 testing coupled to false negative rates as ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Methodology for Identification of Senolytics that Reduce Age-related Disease and Dysfunction

    SBC: Recursion Pharmaceuticals, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): Chronic diseases of aging account for a significant proportion of healthcare spending and result in a painful and limiting existence for many tens of millions of Americans and hundreds of millions of people around the world. Recursion Pharmaceuticals has developed a drug discovery platform that re-purposes known drugs for the treatment of such diseases. The pla ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Clinical Evaluation of a New Middle Ear Diagnostic to Support FDA Regulatory Clearance

    SBC: PHOTONICARE INC            Topic: NIDCD

    PROJECT SUMMARY IntroductionPhotoniCareIncis a medical device company nearing commercializing the ClearViewa handheldoptical imaging device for improved diagnosis of middle ear healthThe purpose of this proposaldeveloped in conjunction with the affiliated FDA review committeeis to perform pivotal clinical studies and use the collected data to establish objective data analysis algorithms for FDAkcl ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. IOBIO based, distributed genomic data access, management, visualization, and analysis

    SBC: FRAMESHIFT LABS INC            Topic: 172

    The precision medicine initiative coupled with advances in genomic research and diagnostics isleading to vast increases in the volume of genomic data being createdwith some estimates statingit will outstrip the storage requirements of YouTube byEnsuring all this data can becost effectively managedand that experts from the biomedicalinformatics and medical disciplinescan easily collaborate on analy ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Indoor Formaldehyde Detection by a Low-Cost Chemical Sensor Based on Organic Nanofibers

    SBC: Vaporsens, Inc.            Topic: 16NCER1A

    Need: People are exposed to formaldehyde, a carcinogen found in building materials. Highly sensitive, real-time formaldehyde sensors would improve human safety by alerting users to harmful concentrations. _x000D_ _x000D_ Technical Feasibility: Vaporsens produces chemical sensors based on novel organic nanofiber technology. Phase 1 results demonstrated high selectivity, rapid-response time, and dem ...

    SBIR Phase II 2018 Environmental Protection Agency
  7. In-Situ Gelling Protein Polymer Intravascular Embolic Agent for Hepatic Carcinoma

    SBC: THERATARGET, INC.            Topic: 102

    SUMMARY This STTR Phase II proposal addresses the significant need for improved treatment options for patients with liver cancerthe fifth highest incidence of cancer in the worldBecause of the lack of symptomshepatocellular carcinomaHCCis detected at advanced stages inof casesfor which theyear survival rate isand atyears it isThe only curative option for advanced HCC is surgical liver resection an ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Clinical optical coherence tomography for retinal metabolic imaging

    SBC: OPTICENT, INC.            Topic: NEI

    PROJECT SUMMARY Diabetic retinopathyDRis a complication of diabetes and a leading cause of blindness in the worldAlthough it is widely accepted that DR is driven by ischemiathe current grading of DR severity is based only on structural alterations such as the presence of abnormal retinal microvasculature in non proliferative DR or angiogenesis in proliferative DRAs a resultmost patients have alrea ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Oral/Topical D-peptide TNF Inhibitors for Inflammatory Bowel Disease

    SBC: NAVIGEN, INC.            Topic: 300

    Project SummaryInflammatory bowel diseaseIBDaffects millions worldwideIBD can be divided into Crohn s DiseaseCDand Ulcerative ColitisUCboth of which are characterized by chronic inflammation in the gutleading to diarrheaulcerationbleedingand in many cases tumorsCurrentlymild to moderate IBD is treated orally with aminosalicylatesASAwhile more severe cases require the use of systemic immunosuppress ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. A real-time, cost-effective, accurate UV measurement and sun protection system to prevent and reduce the incidence of sunburn in high-risk consumers.

    SBC: WEARIFI, INC.            Topic: 100

    TBD

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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