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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nezavist a Novel Molecule for Treatment of Alcohol Use Disorder

    SBC: LOHOCLA RESEARCH CORPORATION            Topic: 150

    Abstract for Supplement ApplicationThe ultimate goal for our original project was to complete the proof-of-concept work, and the multitude of pharmacodynamic, pharmacokinetic, toxicokinetic, safety, and toxicology studies required by the FDA to apply for an IND. We are fully satisfied that we have generated a new chemical entity that acts at a novel binding site on the GABA-A receptor and acts in ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Continuous Monitoring of COVID-19 Symptomatology for Elderly Patients in Long Term Care Facilities Using Advanced, Soft, and Flexible Sensors Mounted on the Suprasternal Notch

    SBC: Sonica LLC            Topic: NIA

    PROJECT SUMMARY: COVID-19 is significantly more lethal in the elderly1 with the greatest risk in those cared for in long-term care facilities (LTCs) where mortality rates range from 19% to 72% worldwide. Monitoring COVID-19 infections in LTCs remains a particular challenging. The existing and a continued expected shortage of sufficient molecular COVID-19 testing coupled to false negative rates as ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Clinical Evaluation of a New Middle Ear Diagnostic to Support FDA Regulatory Clearance

    SBC: PHOTONICARE INC            Topic: NIDCD

    PROJECT SUMMARY IntroductionPhotoniCareIncis a medical device company nearing commercializing the ClearViewa handheldoptical imaging device for improved diagnosis of middle ear healthThe purpose of this proposaldeveloped in conjunction with the affiliated FDA review committeeis to perform pivotal clinical studies and use the collected data to establish objective data analysis algorithms for FDAkcl ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Clinical optical coherence tomography for retinal metabolic imaging

    SBC: OPTICENT, INC.            Topic: NEI

    PROJECT SUMMARY Diabetic retinopathyDRis a complication of diabetes and a leading cause of blindness in the worldAlthough it is widely accepted that DR is driven by ischemiathe current grading of DR severity is based only on structural alterations such as the presence of abnormal retinal microvasculature in non proliferative DR or angiogenesis in proliferative DRAs a resultmost patients have alrea ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. A real-time, cost-effective, accurate UV measurement and sun protection system to prevent and reduce the incidence of sunburn in high-risk consumers.

    SBC: WEARIFI, INC.            Topic: 100

    TBD

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. The Association of Late-Life Depression, Cognitive Functioning, and Sleep Disorder in Aging

    SBC: ACTIVAS DIAGNOSTICS, LLC            Topic: NIA

    Abstract There is an urgent need for new diagnostic approaches for early identification and progression in Alzheimer s diseaseADand related dementiasADRDNIA s Strategic Direction C and D to improve our understanding and develop interventions for mild cognitive impairmentMCIthe prodrome of ADThis proposal focuses on sleep statusa known hallmark of neurological diseaseand commonly present in MCI ADS ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Advanced Nucleation Technologies for Membrane Protein Crystallization to Accelerate Structure-Based Drug Design for Substance Use Disorders

    SBC: DENOVX, LLC            Topic: NIDA

    PROJECT SUMMARY The goal of this Phase I proposal is to improve membrane protein crystallization outcomes using bifunctionalhydrophilic hydrophobicself assembled monolayersSAMsas a substrate that interacts with the bicelle envelope and indirectly preconcentrates and preorganizes membrane proteins to facilitate nucleation and crystal growthOf thehuman membrane proteins potentially relevant to drug ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Real-time volumetric specimen imager for 3D intra-operative lumpectomy margin assessment

    SBC: CLARIX IMAGING CORP            Topic: 102

    Project Summary We propose to develop a novel volumetric specimen imagerVSIsystem for significantly reducing breast lumpectomy s reoperation rate and improving cosmetic outcomesAmong the annual performance of andgtlumpectomies in the USaboutof patients need reoperationswhen post surgery pathology examination revealspositive marginindicating incomplete tumor removal in initial surgeryCurrently phys ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. PatientCareAnywhere: Patient Support and Empowerment Across the Care Continuum

    SBC: BRIGHTOUTCOME INC.            Topic: 102

    DESCRIPTIONprovided by applicantComprehensive bio psychosocial screeningwhich covers not only physical symptoms and psychosocial issuesbut also practical concerns such as transportationfinanceswork and childcareoffers the true opportunity to maximize the benefits of medical care and social support to patients and their families while enhancing operational efficiency and resource management for hea ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Intraoperative Ureter Detection System

    SBC: BRITESEED, LLC            Topic: NICHD

    PROJECT SUMMARY ABSTRACT The goal of this small business innovation research grant is to develop and commercialize a cost effectivecontrast assisted intraoperative ureter detection systemwhich integrates into existing surgical tools to identify ureters in real time and prevent iatrogenic injuriesof iatrogenic ureteral injuries are detected postoperativelyup todays after hospital dischargeThese inj ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
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