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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Formulation and testing of an entirely wood-based exterior insulation board for the high-performance building market

    SBC: GO Lab Inc.            Topic: 17NCER6B

    The goal of this project is the formulation a rigid, insulating, low-density wood composite, with physical and thermal properties comparable to fossil fuel derived foams. _x000D_ _x000D_ To achieve energy conservation standards mandated by certification agencies such as Passive House and LEED, high performance buildings require multiple shells of insulation – an inner shell that contains electri ...

    SBIR Phase I 2018 Environmental Protection Agency
  2. Clinical optical coherence tomography for retinal metabolic imaging

    SBC: OPTICENT, INC.            Topic: NEI

    PROJECT SUMMARY Diabetic retinopathyDRis a complication of diabetes and a leading cause of blindness in the worldAlthough it is widely accepted that DR is driven by ischemiathe current grading of DR severity is based only on structural alterations such as the presence of abnormal retinal microvasculature in non proliferative DR or angiogenesis in proliferative DRAs a resultmost patients have alrea ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. A Therapeutic Wearable Sensor for Dysphagia

    SBC: Sonica LLC            Topic: NIA

    PROJECT SUMMARYOf themillion individuals worldwide with Alzheimer s disease and related dementiasADRDtotomillion individualssuffer dysphagia or swallowing problemsThe sequelae of dysphagia in this vulnerable population include malnutritiondehydrationand aspiration pneumoniaSince swallowing and breathing share a common anatomical pathwayprecise coordination is criticalIn normal individualsswallowin ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Surefooted Fall Simulation Training

    SBC: Surefooted LLC            Topic: NIA

    PROJECT SUMMARY ABSTRACT Surefooted LLC is developing a novel type of physical therapy equipment with the potential to revolutionize fall preventionthe Surefooted TrainerTrainerinsenior citizens experience a fall each year and falls are the leading cause of death by an injury among those agedand olderCurrent treatments to prevent falls are inadequateThe Trainer consists of abyfoot platform with in ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Optimizing Direct Delivery of Nucleic Acid Therapeutics

    SBC: FHC, INC.            Topic: NIMH

    Project Summary While nucleic acid therapeutics have shown promise in rodent and nonhuman primate models of CNS diseasesall double blind clinical trials to date have failedOne likely explanation for this failure is poor therapeutic distribution in targeted brain regionsFor examplepost mortem studies of patients with Parkinsonandapos s Disease receiving intraparenchymal injections of AAV NTN demons ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A real-time, cost-effective, accurate UV measurement and sun protection system to prevent and reduce the incidence of sunburn in high-risk consumers.

    SBC: WEARIFI, INC.            Topic: 100

    TBD

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy

    SBC: Enzyme by Design Inc.            Topic: 102

    PROJECT SUMMARY Enzyme by DesignIncEbDis developing a safer version of L asparaginase that can be used routinely in the treatment of adult ALL patients whose hypersensitivity to todayandapos s bacterial L asparaginases deprives them from this efficacious therapyEbDandapos s L asparaginase is novel due to its mammalianguinea pigorigin and its lack of L glutaminase co activityThe need for better the ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. The Association of Late-Life Depression, Cognitive Functioning, and Sleep Disorder in Aging

    SBC: Activas Diagnostics, LLC            Topic: NIA

    Abstract There is an urgent need for new diagnostic approaches for early identification and progression in Alzheimer s diseaseADand related dementiasADRDNIA s Strategic Direction C and D to improve our understanding and develop interventions for mild cognitive impairmentMCIthe prodrome of ADThis proposal focuses on sleep statusa known hallmark of neurological diseaseand commonly present in MCI ADS ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Intraoperative Ureter Detection System

    SBC: BriteSeed, LLC            Topic: NICHD

    PROJECT SUMMARY ABSTRACT The goal of this small business innovation research grant is to develop and commercialize a cost effectivecontrast assisted intraoperative ureter detection systemwhich integrates into existing surgical tools to identify ureters in real time and prevent iatrogenic injuriesof iatrogenic ureteral injuries are detected postoperativelyup todays after hospital dischargeThese inj ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Clinical Evaluation of a New Middle Ear Diagnostic to Support FDA Regulatory Clearance

    SBC: PhotoniCare, Inc.            Topic: NIDCD

    PROJECT SUMMARY IntroductionPhotoniCareIncis a medical device company nearing commercializing the ClearViewa handheldoptical imaging device for improved diagnosis of middle ear healthThe purpose of this proposaldeveloped in conjunction with the affiliated FDA review committeeis to perform pivotal clinical studies and use the collected data to establish objective data analysis algorithms for FDAkcl ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health

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