Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Computer-based Prescription Opioid Abuse Prevention for Adolescents

    SBC: HEALTHSIM, INC.            Topic: R42

    DESCRIPTION provided by applicant Recreational use of prescription opioids among adolescents is a significant and growing public health concern and has been referred to as an emerging epidemic in the U S Although a number of science based interactive drug abuse prevention programs exist focused on preventing use of non prescription drugs among youth to our knowledge no science based inter ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Fluorescence Image-Guided Near Infrared (NIR) Photodynamic Therapy (PDT) Agent

    SBC: PHOTOLITEC LLC            Topic: 102

    DESCRIPTION provided by applicant Photolitecandapos s patented technology is focused on developing improved agents for tumor imaging image guided surgery and or photodynamic therapy PDT The proposed STTR proposal includes fluorescence image guided PDT a andquot See and Treatandquot approach The fluorescence imaging compound with long wavelength absorption near nm should be extremel ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Development and in vitro validation of therapy for mucopolysaccharidosis III

    SBC: Phoenix Nest Inc.            Topic: 105

    DESCRIPTION provided by applicant Sanfilippo disease mucopolysaccharidosis type III MPS III is a devastating neurodegenerative lysosomal storage disorder of childhood for which there is no cure or effective treatment available The fundamental cause of MPS III is an inherited mutation in one of the enzymes required to catabolize heparan sulfate HS a glycosaminoglycan which plays importa ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Dityrosine Locked Prefusion F Protein: A Path To A Protective RSV Vaccine

    SBC: AVATAR MEDICAL, LLC            Topic: NIAID

    DESCRIPTION provided by applicant The pre fusion conformation of the RSV F protein preF is the primary determinant of neutralization in immunized sera However this conformation is unstable and rapidly transitions to the postfusion conformation A disulfide stabilized prefusion variant with cavity filling mutations DS Cav has been shown to yield high neutralizing titers in animals howeve ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Ultra-low dose Influenza vaccines

    SBC: Codagenix Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Current seasonal Influenza vaccines are proving to be ineffective especially in at risk populations For example this yearandapos s inactivated flu vaccine had only a efficacy rate against H N infections in the elderly and the current live attenuated Influenza vaccine LAIV is aged restricted for those above years of age Therefore there is glaring un ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. A Novel Recombinant Protein for Mitigating Total Body Radiation Injury

    SBC: THERASOURCE, LLC            Topic: NIAID

    DESCRIPTION provided by applicant This SBIR Phase I proposal is intended to demonstrate the feasibility of developing a novel and effective therapeutic agent for acute radiation injury The threat of nuclear terrorism remains high and there is a possibility of a nuclear power plant leak both of which can cause acute radiation injury at a large scale Currently there are no therapeutic agents ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Enhancing engraftment of cord blood for treatment of neoplastic disorders

    SBC: Marrowsource Therapeutics International LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Hematopoietic stem cell transplantation is a form of stem cell therapy used to treat cancers such as lymphoma and leukemia and other blood related diseases However there currently are several drawbacks in the use of bone marrow hematopoietic cell transplantation Most importantly the donor pool is limited by the need for at least partial HLA matching and t ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a Clinically Viable Pattern Recognition Embedded System

    SBC: Coapt LLC            Topic: NICHD

    DESCRIPTION provided by applicant Pattern recognition PR myoelectric control systems can dramatically improve an amputee patientandapos s control of a powered prosthesis but they have not been made commercially available Coapt LLC is a start up stage company that has initiated a controlled commercial release of PR myoelectric control for the benefit of upper limb amputees The controlle ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. IntelliWheels: The Automatic Transmission for Manually Propelled Wheelchairs

    SBC: IntelliWheels, Inc.            Topic: 22

    DESCRIPTION provided by applicant IntelliWheels automatic gear shifting wheels represent a significant paradigm shift as the first ultra light affordable and intuitive way to mke pushing a wheelchair easier The manual wheelchair user mWCU still pushes the hand rims in any direction however the hand rims drive the transmissions located in each wheel hub which in turn drive the wheels ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Development of an Antigen Capture Assay for Babesia microti

    SBC: Biopeptides, Corp            Topic: NIAID

    DESCRIPTION provided by applicant Babesia microti the primary etiologic agent of human babesiosis is a tick borne eukaryotic apicomplexan pathogen that is an increasing threat to the US public health Although B microti is primarily a tick borne pathogen it can be transmitted by transfusion of infected blood Despite the well recognized threat there is no FDA licensed test to screen donor ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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