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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. TOPIC 363: myCare2- Supporting Caregivers and Caregiving

    SBC: BRIGHTOUTCOME INC.            Topic: NCI

    The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Assay optimization and adaptation for a customized meter development

    SBC: GlucoSentient, Inc            Topic: NIAID

    Invasive fungal infectionsIFIcaused by ubiquitous mold and yeast is a common cause of negative health outcomes for immunocompromised patientsincluding patients undergo solid organ transplantSOTand hematopoietic stem cell transplantHSCTregularly leading to events such as organ failure or deathCurrent methods for screening IFI rely on laboratory tests that require specialized equipment and professio ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Reverse Engineering- Light, Dome: NIIN 015639517

    SBC: Breault Research Organization, Inc.            Topic: DLA171002

    The trend over the last several years is fewer businesses supplying manufactured products. Thus, by supply and demand, the cost of military hardware has increased with less competition. Furthermore, amortized cost of the qualifying a new product becomes cost prohibited resulting in non-competitive bids compared to historical averages. DLAs Replenishment Parts Purchase or Borrow program supports re ...

    SBIR Phase I 2018 Department of DefenseDefense Logistics Agency
  4. Randomized Prospective Phase II Clinical Trial of NVX in Association with Chemoradiation of Glioblastoma

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Glioblastoma multiforme GBM is a malignant primary brain tumor affecting about new cases per year in the U S Average survival is only about months Radiation RT is most commonly administered as fractions of Gray each over weeks with concomitant temozolomide TMZ GBM tumors are hypoxic The primary mechanism of RT is creation of singlet oxygen hypoxia within GBM adversel ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. A Metabologenomics Platform for Large Scale High Throughput Natural Product Discovery

    SBC: Microbial Pharmaceuticals, Inc.            Topic: NCCIH

    ABSTRACT The estimates of natural product producing gene clusters within the genomes of microorganisms are far greater than the number of known natural products indicating that there is a wealth of untapped molecules within these organisms that offer huge potential as leads for new medicines Unfortunately the prevailing paradigms for natural product discovery are ill suited for accessing this ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. A rapid and portable test for home monitoring of phenylalanine levels by patients with phenylketonuria using a blood glucose meter

    SBC: GlucoSentient, Inc            Topic: NICHD

    Project Summary Abstract Phenylketonuria PKU is a serious inborn metabolic disorder affecting out of every children born in the U S annually Characteristic effect of PKU is the impaired capability of the body to convert the amino acid phenylalanine Phe to tyrosine and as a result Phe level is elevated in the blood stream While Phe is required for normal growth and brain developm ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Disaggregation of Toxic Protein Oligomers in Brain with Electromagnetic Treatment

    SBC: NeuroEM Therapeutics, Inc.            Topic: 104

    ABSTRACT Formation of misfolded protein oligomers in neurons is an early and causative event in a variety of neurodegenerative diseases such as Alzheimer s Disease amyloid and tau oligomers Fronto temporal lobe dementia tau oligomers and Parkinson s Disease synuclein oligomers These toxic oligomers share a common aggregation mechanism that involves formation of hydrogen bonds betwee ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Application of PPODA QT for embolization of aneurysms

    SBC: Aneuvas Technologies, Inc.            Topic: 101

    A cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brain Often going unnoticed and untreated an aneurysm can cause a sudden and catastrophic hemorrhage or stroke Approximately of patients die from an aneurysm rupture even before receiving medical attention and of patients die despite medical treatment Patients that survive typical ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Regulators of NaV Channels Novel Anti Allodynic Drug Candidates

    SBC: Regulonix            Topic: 102

    PROJECT SUMMARY Chemotherapy induced peripheral neuropathy CIPN is a common prevalence and potentially dose limiting side effect of many cancer chemotherapy drug treatment regimens Clinically CIPN presents with pain that is burning shooting or electric shock like The increase in prevalence of cancer coupled with an increase in the cancer survival rates due to chemotherapy regimens ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Dodecafluoropentane Prevents Ischemia Reperfusion Injury in Contemporary Acute Myocardial Infarction Management

    SBC: NUVOX PHARMA, L.L.C.            Topic: NHLBI

    Due to multiple factors time to administration of lytic therapy or emergent percutaneous coronary intervention PCI in acute ST segment elevation myocardial infarction STEMI may be delayed resulting in loss of additional myocardial tissue These delays are virtually impossible to overcome in remote regions and are associated with increased mor ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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