Award Data

"At 2.7 million miles of paved roads, the United States has the largest network of roads in the world. The mainstream approach to pavement rehabilitation has been to mill the deteriorated asphalt and replace with new asphalt mix. The hot in-place pavement recycling process has the potential of replacing the milling and resurfacing process with substantial financial and environmental savings. Ho ...

"As part of its mission to protect human health and the environment, the U.S. Environmental Protection Agency is dedicated to developing and promoting innovative cleanup strategies that restore contaminated sites to productive use, reduce associated costs, and promote environmental stewardship. However, in adopting this strategy there will be an increasing need to implement a more cost effective, ...

"The environmental Protection Agency is soliciting innovations for the development of small unit drinking water systems that will inactivate contaminants including pesticides, organic pollutants, pharmaceuticals, personal care products, and pathogens. In the US, 85% of all public water systems serve fewer than 3,300 people, thus these water systems are considered small. For providing these small ...

This Small Business Innovation Research (SBIR) project will develop and ready for commercialization a scalable, low-cost process for purification of water containing Contaminants of Emerging Concern (CECs) using anodic oxidation with boron-doped ultrananocrystalline diamond (UNCD®) thin films. Resent research demonstrated that there is considerable potential for the development of electrochemica ...

DESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNTs) are the most potent protein toxins known. Given their potent toxicity and their potential use in bio-warfare scenarios, BoNTs are included among the Category A select agents. The currentlyavailable pentavalent toxoid vaccine requires multiple boosters before being effective, and protects unequally against the different BoNT serotyp ...

DESCRIPTION (provided by applicant): Improved diagnosis of Neisseria gonorrhoeae (GC) infections represents a critical unmet medical need. The CDC estimates that approximately 700,000 people are infected by GC annually, with approximately half of these cases reported. The clinical spectrum of GC infection includes urethritis and cervicitis, pelvic inflammatory disease (PID), and disseminated disea ...

DESCRIPTION (provided by applicant): The innovation presented in this proposal is a new class of label-free biochemical sensors with applicability in point of care (POC) medical diagnostics. The goal of the project to develop commercial biochip systems with compelling performance metrics targeted for rapid screening of an array of antibiotic resistant microbials in a clinical setting. The biochips ...

DESCRIPTION (provided by applicant): We propose the development of a user (surgeon) friendly time efficient and cost effective system for accurate and repeatable intraoperative patient-specific THA component positioning based on a new paradigm of accelerometer and gyroscope inertial measurement units (IMUs) using newly patented and patent pending technologies. The successful development of this pr ...

DESCRIPTION (provided by applicant): According to the Center of Disease Control and Prevention, arthritis is the greatest single cause of chronic pain and disability among Americans .2,3 Currently there is no cure for osteoarthritis, only medication and surgical procedures are available to alleviate the pain and discomfort associated with this degenerative bone disease. Current surgical treatment ...

DESCRIPTION (provided by applicant): Claustrophobia and disruptive patient motion are common impediments to MRI examination, but they may be prevented or ameliorated with a non-pharmacologic behavioral intervention administered by trained staff. The potential benefits of such an intervention are highly significant, considering that the alternatives are to cancel the study or administer sedation. I ...