Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to improve the way educators and therapists teach social skills to children who are on the autism spectrum (as well as those affected by other social skills disorders) and deliver cost efficiencies that could expand access to such support across diverse socioeconomic classes and geographica ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is the development of a digital skeletal evaluation workflow for reproductive toxicology studies that will better ensure that potential therapeutics with teratogenic effects will not make it to the marketplace, and at reduced time and cost. The current approach for characterizing the impact of new the ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project will be to develop protein purification nanotechnology and materials for biopharmaceutical applications. Over 150 different protein or small peptide-based drugs have received FDA approval to treat an array of diseases (e.g., biologics, monoclonal antibodies, and blood clotting factors). Protein purifi ...

This SBIR Phase I project seeks to transform treatment regimens for individuals suffering from malaria infections. Malaria, particularly caused by Plasmodium vivax (P. vivax) and Plasmodium ovale (P. ovale) remain a potential cause of morbidity and mortality amongst the 2.85 billion people living at risk of infection. The only drug currently available for treatment therapy for P. vivax and P. oval ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is an improvement in how artificial limbs (prostheses) are fitted to the individual user. This promises better rehabilitation outcomes for people with limb loss, which lowers the risk of long-term health issues, such as accidental falls, back pain, or conditions that are associated with a sede ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is the restoration of trust in computing systems. Successful cyberattacks, including mass privacy breaches and the discovery of device backdoors, have shaken trust in computing, put users at risk, hurt the economy, and even threatened our national security. The usual set of ad-hoc, incomplete, ...

This SBIR Phase I project aims to prove the technical feasibility and the economic viability of natural fiber welded and dyed yarns and fabrics. Natural fiber welding is process that swells and mobilizes polymers within natural fibers to create higher performance yarns and fabrics. At sufficiently fast rates, individual fibers are fused and bonded together without glues or resins while retaining a ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to develop and bring to market tools that improve code quality and help avoid dangerous bugs, while also improving programmer productivity. Poor code quality leads to bugs which often translate into financial loses and can even endanger human life. A study by NIST estimated software bugs co ...

This SBIR Phase I project proposes to develop a novel cancer targeting technology, Active Tissue Targeting via Anchored ClicK Chemistry (ATTACK), for targeted treatment of triple negative breast cancer (TNBC). TNBC is a subtype of breast cancer that occurs in 10-20% of diagnosed breast cancers and is more likely to affect younger people, African Americans, Hispanics, and those with BRCA1 gene muta ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is that it will save billions of dollars by anticipating construction delays and streamlining coordination to prevent them. Lower costs will help upgrade our nation's infrastructure, which is a critical national priority. Many construction companies strongly want a solution to indoor progress ...