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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 5996 results
  1. Development and Optimization of MNK Inhibitors for the Treatment of Neuropathic Pain

    SBC: 4E THERAPEUTICS, INC.            Topic: 104

    Abstract The goal of this project is to develop an optimized MNK inhibitor for neuropathic pain treatment. MNK is a kinase that phosphorylates eIF4E to control the translation of a distinct subset of mRNAs. Our focus on this target for neuropathic pain is grounded in evidence that MNK-eIF4E signaling is activated in nociceptors upon exposure to pain promoting cytokines and growth factors as well a ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  2. Clinical Vector for TCR Immunotherapy Targeted to Melanoma

    SBC: LENTIGEN CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): This Phase II proposal is a continuation of our Phase I award, Lentiviral Vectors for TCR Immunotherapy Targeted to Melanoma. We have successfully achieved the milestones laid out in our initial application. We generated a lentiviral gene vector capable of expressing a T cell receptor (TCR) specific for the tyrosinase:368-376 epitope, and demonstrated the act ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  3. VGo-Assist, A Mobile Telepresence Robot to Engage Persons with Alzheimer's Disease and Related Dementias

    SBC: VECNA TECHNOLOGIES, INC            Topic: NIA

    Project Summary/Abstract Assistive Technologies (AT) is a broad area of activities to support physical health, well-being, social connectedness, and ability to live independently at home. Assistive Robotics (AR) has largely referred to robots that assisted people through physical interaction, while Socially Interactive Robotics (SIR) describe machines that interact primarily through social interac ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Inhaled Vancomycin for Treatment of MRSA Infections in CF

    SBC: SAVARA INC.            Topic: NHLBI

    DESCRIPTION provided by applicant Persistent respiratory methicillin resistant Staphylococcus aureus MRSA infections have become increasingly common in cystic fibrosis CF patients with a prevalence of almost in CF patients in the US This is concerning as MRSA positivity is associated with a faster decline of lung function and a years shorter median life expectancy compared to CF p ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Preclinical Development of a Novel Therapeutic to Rejuvenate Aging Muscle Stem Cells and Enhance Muscle Strength and Function Post Hip Fracture

    SBC: RIDGELINE THERAPEUTICS LLC            Topic: NIA

    Muscle-aging is defined by progressive declines in mass and strength that poses a high risk for falls, fatal injury, and trauma-related fractures among older Americans (age 60+). Each year, rt30% of older adults suffer a fall, resulting in ~2.8 million traumatic fractures that significantly reduce mobility, independence, overall health, and quality of life for the elderly. Among fall-related injur ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  6. Improved AD/ADRD Assessment Sensitivities Using a Novel In-Situ Sensor System

    SBC: Birkeland Current LLC            Topic: NIA

    Project Summary/AbstractAccurate assessment of daily functions for individuals at risk for and with AD/ADRD, is fundamental to detection, diagnosis, and characterization of its progression and prescribed treatments. Current assessment techniques typically rely on non- continuous, discreet observations provided from a third party and covering single or limited performance domains. With significantl ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  7. ARPA-H-01 TOPIC: STREPAPP: DEEP LEARNING TO DIAGNOSE STREPTOCOCCAL PHARYNGITIS

    SBC: AUSCULTECH DX LLC            Topic: AH01

    This Phase II project is for the advancement of diagnostic capabilities for detecting Group A Streptococcus pharyngitis (GAS). The goals under the contract include a comprehensive and diverse database, multiple trained and optimized deep learning models deployable on a mobile device, FDA clearance for the algorithms, and the validation of the app's performance through clinical research. These achi ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Development of VLP vaccine for RSV

    SBC: SIGMOVIR BIOSYSTEMS, INC.            Topic: NIAID

    Respiratory syncytial virus (RSV) is a significant human pathogen severely impacting neonates and young children, but no vaccine exists to protect this vulnerable population. Furthermore, direct vaccination of neonates is likely ineffective due to the immaturity of their immune system, and neonate immunization is potentially unsafe. The current view is that maternal vaccination is the best and saf ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Finalizing and Testing an Online Therapist Training and Assistance Program to Facilitate Implementation of Comprehensive Behavioral Intervention for Tic Disorders (CBIT-Trainer)

    SBC: PSYC Tech, Ltd.            Topic: 104

    Abstract (Project 2R44MH111450-03A1) Tic disorders (TDs) are a class of neurodevelopmental disorders characterized by involuntary motor and vocal tics1 that affect 1%-3% of the population2 and cause substantial distress, interference and disability.3-9 Comprehensive Behavioral Intervention for Tics (CBIT) is an empirically-validated collection of behavioral tic management techniques that is now in ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  10. Commercialization Readiness Pilot for Amplifying Fibrinolysis in Ischemic Stroke

    SBC: TRANSLATIONAL SCIENCES INC            Topic: 103

    Ischemic stroke is the second leading cause of death and disability worldwide. Tissue plasminogen activator (TPA), the only approved treatment for ischemic stroke, dissolves the culprit fibrin thrombus to restore blood flow and relieve the brain from ischemia. Unfortunately, after prolonged ischemia, TPA restores full blood flow in only 30% of patients and may cause serious or fatal complications; ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
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