Award Data

Additive manufacturing has delivered enormous advantages in rapidly producing prototype designs for both the industrial and military sectors. However, the true promise of transitioning from prototype to production of essential 3D printed components using high-performance materials has remained untenable. The High Speed Extrusion (HSE) process developed by Essentium flips this longstanding paradigm ...

The ability to rapidly deploy shelter is critical to a lethal and resilient force. New and innovative technologies are needed to advance the capabilities of Air Force civil engineers and RED HORSE units. ICON is developing a technology that could offer a step advance in the ability of expeditionary teams to rapidly deploy shelter and base defenses using 3D printing of concrete structures. Potentia ...

Abstract The goal of this project is to develop an optimized MNK inhibitor for neuropathic pain treatment. MNK is a kinase that phosphorylates eIF4E to control the translation of a distinct subset of mRNAs. Our focus on this target for neuropathic pain is grounded in evidence that MNK-eIF4E signaling is activated in nociceptors upon exposure to pain promoting cytokines and growth factors as well a ...

DESCRIPTION (provided by applicant): This Phase II proposal is a continuation of our Phase I award, Lentiviral Vectors for TCR Immunotherapy Targeted to Melanoma. We have successfully achieved the milestones laid out in our initial application. We generated a lentiviral gene vector capable of expressing a T cell receptor (TCR) specific for the tyrosinase:368-376 epitope, and demonstrated the act ...

Ultra-light weight, highly conductive carbon nanotube sheets that can be bonded to graphite composites while also conducting in the GHz region have potential to broadly improve EMI/ESD systems. These materials have additional applications including: EMI cable shielding, EMI/EMP electronics protection, preventing unwanted EMI emissions, highly conductive ground planes, and ESD layers. This proposa ...

Technology Service Corporation (TSC) will develop innovative waveforms and exploitation algorithms for concurrent synthetic aperture radar (SAR) and moving target indication (MTI) in contested RF environments to counter emerging threats from commercial un

ABSTRACT: Crossfield Technology proposes a Fermi Cluster for Real-Time Hyperspectral Scene Generation. The system architecture features heterogeneous processors for real-time scene generation, a high-throughput (10-40 Gbps), very-low-latency communications fabric, and a synchronous hyperspectral projector interface. A multi-core communications processor with an FPGA coprocessor provides a real-ti ...

ABSTRACT: Current methods for inspecting aircraft engine inlet and exhaust cavities are labor intensive and error prone. Airmen crawl into ducts looking for defects, trace suspected sites on Mylar sheets noting their position relative to cavity features, and manually enter the data into an aircraft assessment system. Technology that can reduce inspection times and eliminate sources of human err ...

Project Summary/Abstract Assistive Technologies (AT) is a broad area of activities to support physical health, well-being, social connectedness, and ability to live independently at home. Assistive Robotics (AR) has largely referred to robots that assisted people through physical interaction, while Socially Interactive Robotics (SIR) describe machines that interact primarily through social interac ...

DESCRIPTION provided by applicant Persistent respiratory methicillin resistant Staphylococcus aureus MRSA infections have become increasingly common in cystic fibrosis CF patients with a prevalence of almost in CF patients in the US This is concerning as MRSA positivity is associated with a faster decline of lung function and a years shorter median life expectancy compared to CF p ...