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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Cryopreservation and delivery of sporozoite vaccine

    SBC: SANARIA INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Malaria causes 500 million clinical cases and gt 1 million deaths annually, is responsible for a loss of gt 1.3% of GDP in Africa annually, and is a serious concern for travelers and the military. A vaccine would be the ideal preventive and is perhaps the only intervention that could facilitate eradication of the disease. When attenuated P. falciparum sporozoi ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Image-Guided Stereotactic Radiosurgery of Breast Cancer

    SBC: XCISION MEDICAL SYSTEMS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Breast cancer is the most prevalent malignancy among women. Its awareness and screening have resulted in the majority of breast cancers being diagnosed in the early-stage, for which breast conservation therapy (BCT) has become the standard of care. BCT consists of a lumpectomy followed by 6-8 weeks of radiation therapy, mostly irradiating whole breast. Althoug ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Robust Classification Methods for Categorical Regression

    SBC: MARTINGALE RESEARCH CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Improving statistical methods to provide better classification performance and new analytical capabilities for categorical regression would be invaluable to the medical and health care research communities. Categorical regression models (e.g., binary logistic, multinomial logistic) are used extensively to identify patterns of alcohol-related symptoms, screen f ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Treatment of Sepsis with Talactoferrin

    SBC: AGENNIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Severe sepsis is a major cause of morbidity and mortality throughout the world. It is the leading cause of death in non-coronary intensive care units (ICUs) in the United States, with more than 750,000 cases occurring every year. This means that in the United States, more than 500 patients die from severe sepsis every day, with 28% to 50% of the patients succum ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Bio-Effects of Ultra-High MRI Gradient Slew Rates

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The spatial resolution and acquisition times for magnetic resonance imaging and spectroscopy could be improved through the application of more powerful and rapid magnetic gradients, thereby potentially leading to improved cardiac imaging and delineation and detection of cancers. Unfortunately, gradient field strength is limited by concerns about potential neura ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Novel mycobacterial translocase I inhibitors- a new class of anti-TB drugs

    SBC: Sequella, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Physicians treating tuberculosis (TB) today are in desperate need of new, efficient, and effective antibiotics to improve both time of treatment and durability of cure in multi-drug resistant (MDR) as well as uncomplica ted TB. In the completed Phase 1 grant (Final Report below), we evaluated an exciting new drug candidate, SQ641. SQ641 has activity superior to ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  7. VALIDATION AND QUANTIFICATION OF FFPE ANTIGEN RETRIEVAL BY PROTEOME ANALYSIS

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Because of the long history of the use of formalin as the standard fixative for tissue processing in histopathology, there are a large number of archival formalin-fixed and paraffin-embedded (FFPE) tissue banks worldwid e. These FFPE tissue collections, with attached clinical and outcome information, present invaluable resources for conducting retrospective pro ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Superagonist Analogs of Recombinant Human TSH for Imaging and Ther

    SBC: TROPHOGEN INC            Topic: N/A

    DESCRIPTION (provided by applicant): Thyroid cancer is increasingly prevalent and the most common malignancy of endocrine tissues, and most patients require lifelong surveillance with diagnostic thyroid-stimulating hormone (TSH)-stimulated radioiodine upta ke as well as thyroid remnant or tumor ablation with radioiodine therapy. The PI, who was both co-inventor and co-developer with Genzyme of wil ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Handheld Three-Dimensional Camera for Wound Healing Monitoring

    SBC: TECHNEST, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose this Phase II SBIR program to further capitalize on the very promising results from our Phase I effort to develop a novel, handheld three-dimensional (3D) camera able to perform objective, quantitative, and t rue 3D measurements of the size, shape, volume, color, and healing status of wounds. Accurate measurement of wound healing enables clinicians t ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Microchips of Protein Kinase Substrates

    SBC: ATACTIC TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This is a SBIR Phase II application for developing microfluidic microchips containing 30k protein kinase (PK) substrate peptides for proteomic PK profiling of cell lysates. In recent years there has been a dramatic expa nsion in our understanding of PK (kinome) biology.1-7 In addition to the fundamental role of PKs in protein post-translational modification and ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
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