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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Diagnostic Influenza RT-PCR Array

    SBC: AKONNI BIOSYSTEMS INC            Topic: N/A

    DESCRIPTION (provided by applicant): Influenza viruses are highly contagious negative-sense RNA viruses cause approximately 114,000 hospitalizations and 20,000 deaths annually. Several drugs are approved by the US Food and Drug Administration (FDA) for treating influenza infections, but successful treatment depends on knowing the specific antigenic subtype and administering these drugs within the ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Production of Adenovector Based Vaccines

    SBC: GENVEC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Adenovirus vectors (Advectors) designed to express an antigenic gene have shown great promise as vaccines. Although GenVec and other groups have constructed numerous Advectors expressing a variety of antigens a substantial subset of antigen genes have been found to be inhibitory to Advector construction and production. This limitation was resolved in our phase ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  3. Stationary Anti-scatter Grids for Digital Breast Imaging

    SBC: CREATV MICROTECH INC            Topic: N/A

    DESCRIPTION (provided by applicant): Breast cancer is the most common cancer among women in the United States and is second only to lung cancer as a cause of cancer-related death. Much of the reduced mortality over the past decade can be attributed to early detection and timely medical intervention. Mammography remains the gold standard for breast cancer screening and early detection. Despite its ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Anaerobically stored red blood cells with extended shelf-life

    SBC: NEW HEALTH SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this project is to develop a novel blood storage system that will extend the shelf life of additive system red cell units, and at the same time, deliver red cells of higher efficacy and lower toxicity for transfusion therapy. In this system, red cells are stored in a modified additive solution under oxygen-depleted condition (anaerobi ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Simulation-Based Wound Closure Training System

    SBC: SIMQUEST INTERNATIONAL, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The pressures of reduced training hours, increased numbers of procedures to master, demands for operating room usage efficiency, and maximizing performance of services whose costs can be recovered has impacted the traditional ways of patient-centric surgeon training. Technology is being increasingly incorporated into the process, especially in minimally invasiv ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  6. Aerosol Delivery of a Recombinant Butyrylcholinesterase BioShield to Protect Ag

    SBC: Plant Vax, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Organophosphorus (OPs) compound are potent neurotoxic chemicals that are widely used in medicine, industry and agriculture; most notably as insecticides. The neurotoxicity which is primarily a result of AChE inhibition, may take the form of cholinergic crisis and death as a consequence of acute exposure or psychiatric symptoms and delayed neuropathy following c ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Small Molecule Therapeutics to Treat Obesity

    SBC: FASGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The morbidity of obesity is a direct result of excess triglyceride accumulation, predominantly in adipose tissue and liver. Particularly in the liver, steatosis contributes to insulin resistance and Type II diabetes, and non- alcoholic steatohepatitis (NASH), which may progress to cirrhosis and liver failure. GPAT (glycerol-3- phosphate acyltransferase) is the ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Ultrasensitive Approaches for Complex Animal Proteomics

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Biologically and clinically relevant proteomic data can only be generated if organ or tissue samples investigated consist of homogeneous cell populations, in which no unwanted cells of different types and/or development stages obscure the results. One of the main problems with the analysis of tissue samples is the heterogeneous nature of the sample. Many differ ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Disposable Respiratory Flow Measurement Device

    SBC: KEY TECHNOLOGIES INC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop, formally benchmark and validate a new flow sensor that will accurately quantify varying degrees of ventilation in pediatric and adult patient populations. The flow sensor is a simple, non-contact, disposable part that provides quantitative measurement of respiratory activity, even in the low-flow range. Current te ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Multiplex Detection of Mutations in Leukemia Patients

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term objective of this project is to develop a comprehensive molecular diagnostic assay for the detection of clinically relevant genetic abnormalities in patients with acute myeloid leukemia (AML), chronic myelogenous leukemia (CML), and myeloproliferative disorders (MPDs). An estimated 44,000 new leukemia cases were predicted for 2008, with more than ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
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