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Award Data
The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of Superactive Analogs of FSH for Human Infertility
SBC: TROPHOGEN INC Topic: NICHDDESCRIPTION (provided by applicant): Infertility affects about 10% of American couples, and there is a very large and rapidly growing market for therapeutics in this field, particularly the primary hormone responsible for ovarian oocyte development, human(h) follicle-stimulating hormone (FSH). Although available urinary and recombinant hFSH products have been quite successful, there is currently a ...
SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Bio-Effects of Ultra-High MRI Gradient Slew Rates
SBC: WEINBERG MEDICAL PHYSICS, INC. Topic: NINDSDESCRIPTION (provided by applicant): This application represents a competing renewal request for a Phase II STTR project, in which we constructed an ultra-fast gradient system for magnetic resonance imaging. Operation of the novel system is based upon theprinciple that the nervous system is relatively insensitive to very short exposures to changing magnetic fields. As a result, we are showing in c ...
STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Attend BIO conference to meet with potential commercialization partners for ultra-fast MRI technology
SBC: WEINBERG MEDICAL PHYSICS, INC. Topic: NINDSDESCRIPTION provided by applicant This application represents a competing renewal request for a Phase II STTR project in which we constructed an ultra fast gradient system for magnetic resonance imaging Operation of the novel system is based upon the principle that the nervous system is relatively insensitive to very short exposures to changing magnetic fields As a result we are showing in ...
STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Wireless Neurostimulation for the Relief of Chronic Neuropathic and Inflammatory
SBC: MICROTRANSPONDER, INC. Topic: NINDSDESCRIPTION (provided by applicant): This is a fast-track proposal to develop a GMP biocompatible microstimulator for implantation into humans for treating chronic pain. The feasibility of using an implanted wireless microstimulator for the treatment of chronic pain will be tested in Phase I. In Phase II we will develop a more sophisticated GMP quality microstimulator for use in humans. The footp ...
SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Microfocused Nanoparticulate ions to enable intracellular molecular imaging.
SBC: IONWERKS INC Topic: NIDADESCRIPTION (provided by applicant): Within the volume of a single cell, lines an extensive amount of information. The current scope of molecular imaging using mass spectrometry typically swamps the cell volume with organic acid matrix just to get observable signals. Herein lies the problem. Putting more matrix that there is analyte (i.e. cellular volume) inherently makes intracellular imaging via ...
SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Multilevel Parallelization of Software for Accurate Protein-Ligand Affinities
SBC: VERACHEM LLC Topic: NIGMSDESCRIPTION (provided by applicant): Many drugs are small molecules that act by binding to a specific protein and thus blocking or altering its actions. For example, the HIV protease inhibitors are important AIDS treatments that work by binding in the active site of the protease enzyme and preventing it from helping to make new viruses. When scientists identify a protein, like HIV protease, as bei ...
SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Development of a low-cost hardware accelerator for 3D image registration
SBC: IGI TECHNOLOGIES, INC Topic: 102DESCRIPTION provided by applicant Our overall goal is to develop a novel computing solution for automatic and accurate registration spatial alignment of dimensional D medical images of any modality and any anatomy rigid or deformable in minute or less Such capability currently does not exist Existing image registration solutions have limited accuracy and or limited applicability p ...
STTR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Preclinical Development of Full Length Single Chain
SBC: PROFECTUS BIOSCIENCES, INC. Topic: NIAIDDESCRIPTION (provided by applicant): The positive outcome of the RV144 Phase III vaccine trial (the Thai trial ) that tested an ALVAC-HIV/AIDSVAX B/E prime/boost protocol has prompted the field to refocus on humoral immunity as a means of achieving sterilizing immunity. This has also renewed interest in positioned other envelope-based subunit immunogens that may provide a better booster to achiev ...
SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Pb-Qdot Direct Gamma Detectors
SBC: WEINBERG MEDICAL PHYSICS, INC. Topic: NCIDESCRIPTION (provided by applicant): A critical property of radiation detectors is stopping power, which describes the efficiency of the detector in collecting radiation. In order to minimize patient dose, it is helpful to increase stopping power, since stopping power is inversely related to the dose required for obtaining high-quality patient images. Stopping power is strongly related to the effe ...
SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health -
Engineered proteases for proteomics
SBC: POTOMAC AFFINITY PROTEIN LLC Topic: NCRRDESCRIPTION (provided by applicant): Proteomics is a rapidly expanding field but current methodologies remain inadequate for achieving its full potential. The most basic enzymological tool for characterizing proteins is the protease. Proteases are alreadyan essential part of proteomic analysis but more sophisticated tools are needed to identify low abundance proteins in highly complex samples. We ...
SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health