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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. In Vitro Culture of Plasmodium falciparum Sporozoites for Malaria Vaccine

    SBC: SANARIA INC.            Topic: R

    DESCRIPTION provided by applicant Sanariaandapos s platform technology is production of aseptic purified cryopreserved Plasmodium falciparum Pf sporozoites SPZ This technology has produced three products administered by needle and syringe all of which are in clinical trials PfSPZ Vaccine radiation attenuated PfSPZ PfSPZ Challenge infectious PfSPZ for controlled human malaria infec ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Genetically Attenuated PfSPZ Malaria Vaccine

    SBC: SANARIA INC.            Topic: R

    DESCRIPTION provided by applicant We build on the successful work in Phase II SBIR R AI in which a genetically attenuated Plasmodium falciparum Pf parasite GAP was produced and shown to generate aseptic Pf sporozoites SPZ that invade hepatocytes but do not replicate We will use this genetically attenuated double mutant parasite deficient in the genes encoding SLARP and B Pf ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Expanding the Market and Success Rates for Myeloablative Cancer Treatments Using PUL an Innate Immune Stimulant

    SBC: PULMOTECT, INC            Topic: NHLBI

    Pulmotect Inc was founded in to translate discoveries that induce innate immune resistance in the lung into therapeutics that will provide protection from inhaled pathogens Our technology platform is a direct result of basic research by our founders on the mechanisms of microbial resistance in the lung epithelium We have developed an inhaled therapeutic PUL that provides immediate p ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Air Barrier System for the Prevention of Prosthesis-related Infections

    SBC: NIMBIC SYSTEMS, INC.            Topic: 300

    DESCRIPTIONprovided by applicantThis project is an evaluation of a novel devicethe Air Barrier SystemABSto reduce the risk of prosthesisrelated surgical site infection in a multi center clinical trialThe ABS shields surgical incisions intra operatively by creating a field of high purity air surrounding an incision that prevents airborne microorganisms from entering the incisionPreliminary findings ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Optimization of a Therapeutic HIVSIV Multi Antigen DNA Vaccine

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: R

    DESCRIPTION The HIV pandemic is one of the greatest public health challenges in history It is estimated that million people are living with HIV and million of those are newly infected In a number of developed countries the risk of death associated with HIV infection has sharply declined due to the use of highly active antiretroviral therapy HAART Unfortunately the rate of new HIV i ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Pilot Human Study Using Transnasal Cooling on Cardiac Arrest Subjects

    SBC: KEY TECHNOLOGIES INC            Topic: NHLBI

    DESCRIPTION provided by applicant This project will result in the creation of a clinical grade product called the CoolStat that will be able to quickly and safely cool the brain and body after cardiac arrest The CoolStat is designed to be initiated by EMS personnel to start early cooling post arrest which has been shown to improve survival rates and neurological outcomes As part of this over ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Physics-Based Simulator to Teach Hands-On Vascular Surgical Skills

    SBC: SIMQUEST INTERNATIONAL, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant SimQuest LLC proposes to develop a physics based vascular surgery skills training simulator that will overcome current shortcomings in experiential open vascular surgery training This dovetails with the mission of the NHLBI to promote application of research results and leverage resources to address public health needs in this case patient safety When the s ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Statistical Mechanics with Quantum Potentials Application to Host Gues

    SBC: VERACHEM LLC            Topic: 100

    DESCRIPTION provided by applicant Host molecules such as cyclodextrins and cucurbiturils can andapos captureandapos smaller molecules and affect their physical and chemical behavior The stronger the host molecule holds onto i e binds its smaller andapos guestandapos the larger the effect ca be Host molecules themselves can also be chemically altered i e derivatized which can change ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Oxygen Mapping System for Enhanced Colonoscopic Neoplasm Detection

    SBC: SURGISENSE CORPORATION            Topic: 102

    DESCRIPTION provided by applicant Ninety five percent of colorectal cancer develops by a well understood series of genetic mutations over a year time frame beginning as a tissue growth commonly termed a polyp Approximately one third to one half of adults will develop one or more polyps over their lifetime approximately ten percent of which will progress to colon cancer Therefore the o ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Late-stage development toward commercialization of multilineage point-of-care Lassa fever diagnostics

    SBC: Zalgen Labs            Topic: NIAID

    DESCRIPTION provided by applicant This project will complete development efforts toward commercialization of multilineage point of care Lassa fever diagnostics Lassa fever LF is a severe often fatal viral hemorrhagic fever VHF Because of its high case fatality rate ability o spread easily by human human contact and potential for aerosol release Lassa virus LASV the causative agent ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
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