Award Data

During the anthrax attacks in 2001, investigators had difficulty in differentiating the strains apart because B. anthracis has a low level of genetic variability. This event demonstrated the need for rapid and precise molecular subtyping technologies. Lynntech proposes to develop an ultra-sensitive quantum dots-based molecular beacon fluorogenic reporter system to identify the presence of specif ...

A semiconductor metrology tool will be developed employing the technique of small-angle x-ray scattering (SAXS) to measure the critical dimension (CD) of patterned device structures. The feasibility of the SAXS technique to measure CD has been shown using high-power synchrotron radiation facilities which are not of practical use to the semiconductor industry. The ultimate project goal is to produc ...

TDI proposes to produce combinatorial GaN and AlGaN samples library having a wide range of doping and fabricated using a variety of surface treatment conditions. These samples will be grown using novel technological approach based on advanced hydride vapor phase epitaxy (HVPE). This method is known to produce bulk GaN materials with low defect density. Recently, TDI has demonstrated high throughpu ...

Chlorinated hydrocarbons represent the most prevalent contaminants in the subsurface, threatening the quality of groundwater at aquifers. Existing technologies for monitoring these contaminants require expensive, labor-intensive methods of sample collection and analysis. The goal of this Phase I research project is to develop a low-cost, compact, reliable, automated, unattended, and long-term mo ...

Chlorinated hydrocarbons represent the most prevalent contaminants in the subsurface, threatening the quality of groundwater at aquifers. Existing technologies for monitoring these contaminants require expensive, labor-intensive methods of sample collection and analysis. The goal of this Phase I research project is to develop a low-cost, compact, reliable, automated, unattended, and lo ...

Some bioterrorism agents cause disease at very low infective doses and their presence can be masked by the environment. Therefore, ultrasensitive detection is required for homeland defense applications. In this Phase I research project, Operational Technologies Corporation (OpTech) proposes to couple DNA aptamers made by the Systematic Evolution of Ligands by Exponential Enrichment (SELEX) proce ...

Some bioterrorism agents cause disease at very low infective doses and their presence can be masked by the environment. Therefore, ultrasensitive detection is required for homeland defense applications. In this Phase I research project, Operational Technologies Corporation (OpTech) proposes to couple DNA aptamers made by the Systematic Evolution of Ligands by Exponential Enrichment (SE ...

Foodborne pathogen detection has always been faced with volume and matrix problems, i.e., low numbers of viral or bacterial pathogens in a large volume of solid or liquid foods that are still potentially infectious. Despite sensitive techniques such as PCR and immunomagnetic-electrochemiluminescence (IM-ECL), there still exists a need to concentrate and semi-purify pathogens from large (liter) vo ...