Award Data

During the anthrax attacks in 2001, investigators had difficulty in differentiating the strains apart because B. anthracis has a low level of genetic variability. This event demonstrated the need for rapid and precise molecular subtyping technologies. Lynntech proposes to develop an ultra-sensitive quantum dots-based molecular beacon fluorogenic reporter system to identify the presence of specif ...

Chlorinated hydrocarbons represent the most prevalent contaminants in the subsurface, threatening the quality of groundwater at aquifers. Existing technologies for monitoring these contaminants require expensive, labor-intensive methods of sample collection and analysis. The goal of this Phase I research project is to develop a low-cost, compact, reliable, automated, unattended, and long-term mo ...

The goal of this Phase I research project is to study a new class of environmentally safe wood preservatives based on cation-anion complexes with antimicrobial activities. The proposed cations include: (1) biguanide/polybiguanide derivatives, (2) polyionenes (polyquats), and (3) quaternary ammonium salts. The associated anions needed to form the complex will be selected from triclosan, tribromo ...

The goal of this Phase I research project is to study a new class of environmentally safe wood preservatives based on cation-anion complexes with antimicrobial activities. The proposed cations include: (1) biguanide/polybiguanide derivatives, (2) polyionenes (polyquats), and (3) quaternary ammonium salts. The associated anions needed to form the complex will be selected from triclosan, ...

Chlorinated hydrocarbons represent the most prevalent contaminants in the subsurface, threatening the quality of groundwater at aquifers. Existing technologies for monitoring these contaminants require expensive, labor-intensive methods of sample collection and analysis. The goal of this Phase I research project is to develop a low-cost, compact, reliable, automated, unattended, and lo ...

Luna will develop a hermetic closure system for use on combat uniforms and shelters that require protection from chemical and biological (CB) warfare agents. Despite great advances in high barrier fabrics, selectively permeable membranes, and unique chemical absorbent technologies, closures for clothing and shelters still possess the greatest risk for chemical or biological breach. Instead of mo ...

The goals of this Phase I research project are to investigate the feasibility of using an artificial neural network (ANN) and an optimization-based water distribution security system ("smart security") for accurately detecting contamination events, and given the nature of the threat, identify optimal crisis management decisions that minimize the threat and maintain a safe water supp ...

Some bioterrorism agents cause disease at very low infective doses and their presence can be masked by the environment. Therefore, ultrasensitive detection is required for homeland defense applications. In this Phase I research project, Operational Technologies Corporation (OpTech) proposes to couple DNA aptamers made by the Systematic Evolution of Ligands by Exponential Enrichment (SELEX) proce ...

The goals of this Phase I research project are to investigate the feasibility of using an artificial neural network (ANN) and an optimization-based water distribution security system (¿smart security¿) for accurately detecting contamination events, and given the nature of the threat, identify optimal crisis management decisions that minimize the threat and maintain a safe water supply. Given th ...

Some bioterrorism agents cause disease at very low infective doses and their presence can be masked by the environment. Therefore, ultrasensitive detection is required for homeland defense applications. In this Phase I research project, Operational Technologies Corporation (OpTech) proposes to couple DNA aptamers made by the Systematic Evolution of Ligands by Exponential Enrichment (SE ...