Award Data

During the anthrax attacks in 2001, investigators had difficulty in differentiating the strains apart because B. anthracis has a low level of genetic variability. This event demonstrated the need for rapid and precise molecular subtyping technologies. Lynntech proposes to develop an ultra-sensitive quantum dots-based molecular beacon fluorogenic reporter system to identify the presence of specif ...

Chlorinated hydrocarbons represent the most prevalent contaminants in the subsurface, threatening the quality of groundwater at aquifers. Existing technologies for monitoring these contaminants require expensive, labor-intensive methods of sample collection and analysis. The goal of this Phase I research project is to develop a low-cost, compact, reliable, automated, unattended, and long-term mo ...

Chlorinated hydrocarbons represent the most prevalent contaminants in the subsurface, threatening the quality of groundwater at aquifers. Existing technologies for monitoring these contaminants require expensive, labor-intensive methods of sample collection and analysis. The goal of this Phase I research project is to develop a low-cost, compact, reliable, automated, unattended, and lo ...

Some bioterrorism agents cause disease at very low infective doses and their presence can be masked by the environment. Therefore, ultrasensitive detection is required for homeland defense applications. In this Phase I research project, Operational Technologies Corporation (OpTech) proposes to couple DNA aptamers made by the Systematic Evolution of Ligands by Exponential Enrichment (SELEX) proce ...

Some bioterrorism agents cause disease at very low infective doses and their presence can be masked by the environment. Therefore, ultrasensitive detection is required for homeland defense applications. In this Phase I research project, Operational Technologies Corporation (OpTech) proposes to couple DNA aptamers made by the Systematic Evolution of Ligands by Exponential Enrichment (SE ...

Foodborne pathogen detection has always been faced with volume and matrix problems, i.e., low numbers of viral or bacterial pathogens in a large volume of solid or liquid foods that are still potentially infectious. Despite sensitive techniques such as PCR and immunomagnetic-electrochemiluminescence (IM-ECL), there still exists a need to concentrate and semi-purify pathogens from large (liter) vo ...

No one questions the philosophy that it is better to avoid industrial pollutionrather than to attempt the clean up of an environmentally abused site.Unfortunately, we are slow to learn this lesson and hazardous wastes become moreexotic and continue to increase. Causing 21 of the 28 EPA superfund sites in theSilicon Valley (Witkowski and Menon 1991), the semiconductor industry was, andcontinues to ...

Industrial wastewater containing toxic waste compound and metal ions pose manyproblems of disposal. The most generally used method of removing metalcontaminants is lime treatment to precipitate metals as hydroxides. The metalis not normally recovered resulting in the need for sludge disposal. The costof sludge disposal plus fewer available disposal sites makes that methodincreasing less attract ...

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