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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Signal Processing for Layered Sensing

    SBC: TOYON RESEARCH CORPORATION            Topic: CBD152006

    As a foundational component of a Layered Sensing architecture, Toyon proposes to develop a Multi-Modal Fusion Module (M2FM) capable ofconfirming detections from Chemical, Biological and Radiological (CBR) sensing networks by fusing together information from other (non-CBR)sensors. The module will provide information to assist operators in confirming an initial CBR detection or rejecting it as a fa ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  2. Extended Release of Pyridostigmine Bromide for Effectively Combating Nerve Agent Exposure

    SBC: INNOSENSE CORPORATION            Topic: CBD181004

    Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigmine bromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it acts as a “temporary” inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitig ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Bi-specific Antibodies Targeting Disease Caused by Encephalitic Alphaviruses

    SBC: BRHMS LLC            Topic: CBD181007

    Highly pathogenic alphaviruses like VEEV/EEV/WWEEV cause encephalitis in humans and equids. These infections are endemic in wide regions of the developing world. Translational research regarding these pathogens is focused on developing new strategies to detect, treat and ideally protect humans and animals from these infections. Gene-encoded antibodies against alphavirus E1/E2 surface proteins will ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Sequential Phase II Proposal for Smartphone Application for Mask Sizing and Projecting Quantitative Fit

    SBC: Physical Optics Corporation            Topic: CBD181006

    To address the Chemical and Biological Defense (CBD) need for a field-portable mass spectrometer for small molecule drugs in clinical samples, Physical Optics Corporation (POC) proposes to develop a new FiEldable DRug Mass Analysis (FERMA) system based on a combination of portable mass spectrometry technology with laser desorption/ionization for use with aqueous clinical samples. The FERMA system ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. Mycotoxin Neutralization Treatment

    SBC: Physical Optics Corporation            Topic: CBD152003

    To address the Chemical and Biological Defense programs (CBDs) need for medical countermeasures against mycotoxin intoxication, PhysicalOptics Corporation (POC) proposes to develop a new Mycotoxin Neutralization Treatment (MyNT). This proposed solution is based on neutralizingmycotoxin from its deleterious effects by acting on multiple levels of mycotoxin metabolism through the novel combination o ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  6. TARGETED THERAPEUTIC ANTIBODY MOLECULES AGAINST VIRAL ENCEPHALITIS

    SBC: BIOO SCIENTIFIC CORPORATION            Topic: CBD161004

    VEEV/EEV/WWEEV are highly pathogenic alphaviruses that cause encephalitis in humans and equids. These infections are endemic in wide regions of the developing world. Translational research regarding these pathogens is focused on developing new strategies to detect, treat and ideally protect humans and animals from these infections. In this Phase I SBIR project, we will establish methodologies for ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  7. Exploiting Microbiome and Synthetic Biology to Discover and Produce Naturally Occurring Antibiotics

    SBC: Radiant Genomics, Inc.            Topic: CBD152004

    In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  8. High Sensitivity, Low Complexity, Multiplexed Diagnostic Devices

    SBC: Paratus Diagnostics            Topic: CBD152005

    Infectious diseases have been a constant cause of non-battlefield injury and illness for military personnel engaged in operations throughout theworld. Detection of these infectious pathogens is critical to proper patient care and management of outbreaks, yet many existing diagnostic testsfail to provide adequate sensitivity and/or simplicity for use in forward locations or in isolated areas. We pr ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  9. Wavelet-Based Approach for Signal Processing and Analysis

    SBC: Physical Optics Corporation            Topic: CBD152006

    To address CBDs need for development of analytical approaches to fuse sensor data from multiple modalities to provide common operationalpictures in threat environments, Physical Optics Corporation (POC) proposes to develop a Wavelet-based Approach for Signal Processing andAnalysis (WASP). WASP is based on novel application of wavelet-based analysis to multimodel, multidimensional data available fr ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  10. Portable System for Sample Preparation and Differentiation of Pathogens at Strain Level

    SBC: LYNNTECH INC.            Topic: CBD04107

    During the anthrax attacks in 2001, investigators had difficulty in differentiating the strains apart because B. anthracis has a low level of genetic variability. This event demonstrated the need for rapid and precise molecular subtyping technologies. Lynntech proposes to develop an ultra-sensitive quantum dots-based molecular beacon fluorogenic reporter system to identify the presence of specif ...

    SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense
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