Award Data

DESCRIPTION provided by applicant Dysregulation of apoptosis pathways and loss of Human Beta Defensin hBD are the common tactics adapted by cancer cells to circumvent the effects of chemotherapy Consequently high dose of chemotherapy is required to obtain a clinically relevant therapeutic index which in turn compromises safety and develops resistance to therapy The problem is acute p ...

DESCRIPTION (provided by applicant): We are developing a novel two-part cold high-level disinfecting/sterilization technology that will be ready to work by mixing in water, just minutes before use. Both components separately are inactive stable derivatives of active high level disinfectant agents, have good shelf life, and easy handling restriction compared to dialdehydes, ensuring the cost-effect ...

DESCRIPTION (provided by applicant): We are developing a novel two-part cold high-level disinfecting (HLD)/sterilization technology that will be ready to work by mixing in water, just minutes before use. Both components separately are relatively inactive,non-toxic and stable chemicals that have good shelf life, and easy handling restrictions compared to the currently used HLD products, ensuring th ...

DESCRIPTION provided by applicant Periodontal bone regeneration requires attention to a the need of a physical barrier to restrict the entry formation of fibro epithelial tissue b he cause of bone loss that is due to hostandapos s inflammatory response to pathological cause and not due to the causative pathogen directly so along with bone regeneration strategies the process also equally ...

DESCRIPTION (provided by applicant): The principal objective of this application is to establish a new methodology for the early detection of abnormal lesions, whether pre-cancerous or cancerous, in breast imaging. Early detection is crucial to identifying lesions while they are still contained when the cure rate is near 100%. Existing mammography often does not identify lesions until significant ...

Early detection of breast cancer is a primary goal in cancer imaging and it is important to identify tumors at an early stage of growth to identify their type. Standard x-ray mammography does not always provide adequate diagnosis; e.g., in cases such as dense or radiation-scarred breasts, and often does not identify tumor presence until significant growth has occurred. Alternative methods are bei ...

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PROJECT SUMMARY Klebsiella pneumoniae is an encapsulated human pathogen capable of causing a myriad of human infections. Recently, K. pneumoniae has also emerged as one the most common causes of secondary bacterial pneumonia in COVID-19 patients. Over the last 40 years, K. pneumoniae has evolved into two distinct pathotypes, known as classical K. pneumoniae (cKp) and hypervirulent K. pneumoniae (h ...

DESCRIPTION (provided by applicant): The broad, long-term objectives and aims of this project are to provide a reliable and easily-used device for qualified health care professionals to screen for and detect heart murmurs produced from congenital and acquired cardiac defects in children and adults. The device will be designed to distinguish between innocent and pathological heart murmurs with a ...

There is a need for new technologies to control restaurant emissions. There are more than 870,000 restaurants in the United States. Most of these restaurants have under-fired charbroilers, creating a significant amount of particulate matter (PM) and volatile organic compounds (VOCs) that have been classified as health and environmental hazards by the U.S. Environmental Protection Agency (EPA). Alt ...