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THE OVERALL GOAL OF THIS PROJECT IS TO DEVELOP A NOVEL, COST-EFFECTIVE CARRIER VEHICLE FOR BOVINE INSULIN-LIKE GROWTH FACTOR (IGF): THE BOVINE IGF CARRIER PROTEIN (BBP3).BBP3 WILL BIND IGF WITH HIGH AFFINITY, PROTECT IT FROM DEGRADATION, AND SLOWLY RELEASE IT IN AN ACTIVE FORM. THEREFORE, BBP3 WILL SIGNIFICANTLY IMPROVE THE BIOACTIVITY OF IGF, PARTICULARLY IN GROWTH PROMOTION, MILK PRODUCTION AND ...

A PHASE I SBIR PROJECT TO INVESTIGATE THE FEASIBILITY OF DEVELOPING AN INTERGENERATIONAL COMMUNITY CARE FACILITY (RESIDENTIAL ELDERLY, DAY CARE CHILDREN) AS AN EMPLOYMENT AND INCOME-GENERATING OPPORTUNITY FOR RURAL AREAS: TO FOSTER, PROMOTE AND IMPROVE THE WELL BEING OF RURAL AMERICANS; TO PROMOTE AND FOSTER IMPROVEMENTS IN SERVICES TORURAL PEOPLE. THE PROPOSED FEASIBILITY STUDY INCLUDES THE FOLLO ...

FLOWER CROP BREEDING PROGRAMS HAVE LAGGED BEHIND FOOD CROP BLEEDING PROGRAMS IN THE IDENTIFICFICATION AND UTILIZATION OF HOST RESISTANCE GENES TO VIRAL, BACTERIAL, AND FUNGAL PATHOGENS, AS WELL AS TO INSECTS AND NEMATODES. CONSEQUENTLY DISSEASE MANAGEMENT IN FLOWER PRODUCTION HAS RELIED HEAVILY ON CHEMICAL CONTROL. THE EXTENSIVE USE OF AGROCHEMICALS SIGNIFICANTLY INCREASES GROWERS' COSTS AND CONTR ...

A PHASE I SBIR PROJECT TO INVESTIGATE THE FEASIBILITY OF DEVELOPING THE EQUIPMENT NECESSARY TO PROVIDE ENHANCED 911 EMERGENCY SERVICE TO RURAL COMMUNITIES. THE PROPOSED PROJECT CONTAINS TWO AREAS: (1) TO MODIFY THE EXISTING PATENTED STATUS RECOGNITIONED UNIT (SRU) TO PERFORM THE TANDEM FUNCTION ON A LOCAL BASIS FOR RURAL COMMUNITIES; AND (2) TO DESIGN AND DEVELOP AN AUTOMATED LOCATION IDENTIFICATI ...

Infectious pancreatic necrosis virus (IPNV) causes an economically significant, untreatable disease in young salmonid fish. A recombinant IPNV subunit vaccine (pTA1) has been developed and consists of a lysate of Escherichia coli cells that expressed IPNV VP2, NS and VP3 proteins. The Phase I research confirmed that the recombinant pTA1 vaccine was effective in laboratory scale trials and indica ...

NOT ALL WILDFIRES CAN BE FOUGHT FROM THE GROUND. MILLIONS OF DOLLARS ARE SPENT EACH YEAR ON AERIAL FIREFIGHTING. A MAJOR PROBLEM CONCERNING THE AERIAL APPLICATION OF FIRE RETARDANTS IS TO ACHIEVE THE OPTIMUM PLACEMENT AND COVERAGHELEVEL (GALLOSN OF RETARDANT PER 100 SQUARE FEET OF GROUND) FOR THE TYPE FUEL AND TERRAIN THE FIRE IS BURNING IN. EXPERIENCED CREWS ARE CAPABLE OF DETERMINING THE APPROPR ...

THE LYGUS BUG IS A MAJOR PEST OF A VARIETY OF CROPS INCLUDING COTTON, SEED ALFALFA AND STRAWBERRIES. CURRENT STRATEGIES RELY ON BROAD SPECTRUM NSETICIDES FOR CONTROL. WHILE THESE INSETICIDES DO REDUCE LYGUS BUG POPULATIONS, SEVERAL UNDESIRABLE SIDE EFFECTS ARE THE RESULT. BIOLOGICAL CONTROL OF OTHER CROP PESTS IS INHIBITED, ENVIRONMENTAL CONTAMINATION CAN OCCUR, AND WORKER SAFETY PROBLEMS ARE EXAC ...

NO DIAGNOSTIC TOOLS EXIST TO DIRECTLY MONITOR THE QUAILITY OF MANUFACTURING PARAMETERS OF PLYWOOD AND OTHER WOOD-BASED COMPOSITES DURING THE PRESSING WHERE ADJUSTMENTS OF TIME, PRESSURE OR TEMPERATURE CAN BE MADE. LACKING SUCH TOOLS, MOST MANUFACTURING GUIDELINES HAVE BEEN DERIVED AFTER-THE-FACT USING TRIAL AND ERROR DESTRUCTIVE AND NONDESTRUCTIVE TESTING METHODS. AS A RESULT, THE PROPERTIES AND F ...

A MOLECULAR SUBUNIT VACCINE TO INFECTIOUS HEMATOPOIETIC NECROSIS VIRUS (IHNV) BASED ON THE VIRAL GLYCOPROTEIN GENE WAS RECENTLY DEVELOPED AND SHOWN TO BE EFFICACIOUS IN PROTECTING SALMONID SPECIES AGAINST VIRAL OUTBREAKS. ALTHOUGH THE VACCINE PRODUCES IMMUNITY AGAINST A NUMBER OF VIRAL OUTBREAKS. ALTHOUGH THE VACCINE PRODUCES IMMUNITY AGAINST A NUMBER OF VIRAL ISOLATES, IT DOES NOT PROVIDE IMMUNIT ...