Award Data

This Small Business Innovative Research (SBIR) Phase I project aims to develop an innovative large-scale photobioreactor for production of natural astaxanthin from Haematococcus strains. The phase I research plan is to construct and evaluate an innovative modular flat-plate photobioreactor for mass culture of the organism. The improved production system, along with a genetically improved Haematoco ...

This Small Business Innovation Research Phase I research project aims to establish "proof-of-concept" of a novel Software Platform directed at needs of FDA's Process Analytical Technologies (PAT) initiative, a framework for innovative pharmaceutical development, manufacturing and quality assurance. PAT is implemented at three levels: Process Understanding; Quality by Design; and Monitor, Predict a ...

This Small Business Innovation Research (SBIR) Phase II project will make the creation of effective intelligent tutoring systems (ITSs) easier, and it will enable the dissemination of that technology to a broader audience than currently realized. ITSs have proven to be highly effective in delivering computer-based instruction, but they have historically been expensive and difficult to build, requi ...

This Small Business Innovative Research (SBIR) Phase I project aims to develop a revolutionary elutriation chamber with the unique ability to select specific cell ranges and then hold these cell in a dispersed, free floating fashion. The selected cells can thus be sorted and decontaminated in a single step. The overall aims are to substitute the current trial and effort approach to cell decontamin ...

This Small Business Innovation Research Phase I research project seeks to develop a novel method of fabricating deep UV LEDs which will allow for wider wavelength ranges as well as provide higher efficiencies than current UV LED technologies. State of the art UV LEDs have wavelength ranges from 255nm to 365nm and are achieved through complex and expensive epitaxial growth of AlInGaN materials. Ext ...

This Small Business Innovation Research (SBIR)Phase I research project will investigate technology innovations needed to support the automated analysis and improvement of the reusability characteristics of digital learning resources. Reusability of digital learning resources is crucial to increasing access and lowering the cost of online training and education. Recent advances in the theory of reu ...

This Small Business Innovation Research (SBIR) Phase I project will develop a compact, robust wavelength sensor for digital control of tunable lasers. During this project the company will design and build a wavelength sensor that can provide an error signal for feedback to a pulsed or cw tunable laser to lock its wavelength. The sensor is based on a novel waveguide circuit, and incorporates no mov ...

This Small Business Innovation Research (SBIR) Phase I project aims to develop a next-generation microsensor for dissolved oxygen (DO) in water. DO sensors are a primary tool for gauging the quality of both fresh water (rivers, lakes, reservoirs) and the oceans; for monitoring the various processes in waste water treatment plants; and, for monitoring fermentation processes in the food and bevera ...

This Small Business Innovation Research (SBIR) Phase II project aims to develop and validate a novel chloroplast transformation vector for protein expression in chloroplasts. The research project will broaden scientific understanding of the parameters of chloroplast transformation by addressing stoichiometric expression of multiple transgenes for effective engineering of pathways such as carotenog ...

The Small Business Innovation Research (SBIR) Phase II project will develop a novel high-resolution instrument capable of penetrating and imaging live cells down to the 50 nm resolution level. This can provide further insights into the molecular makeup of cells and may open new avenues toward the understanding of cellular processes and their modification at a physically visible level as a result o ...