Award Data

Operational Technologies Corporation (OpTech) has completed a successful Phase I SBIR contract in which 124 new candidate DNA aptamer sequences against five different species of rickettsiae were developed and screened by ELISA-like plate assay. Several pi

The need for controlled medical tissue regeneration in trauma or disease therapies has long existed. Only recently, however, has sufficient technology been developed to even begin exploring human applications. A key breakthrough was the discovery of the stem cell as a significant element for regeneration. Previous work has suggested that stem cells can be targeted and captured in a synthetic micro ...

The ability to direct the wound pathways following injury could provide a critical path in wound care at crucial times during the progression of healing. A promising field of study in wound healing is epigenetics; alterations in gene expression caused by mechanisms other than changes in DNA sequence. Identification of epigenetic factors and their manipulation may result in the development of nov ...

Detection of chemical and biological threats is becoming increasingly important in today"s world of asymmetric enemies. The threat of attack using chemical and biological warfare (CBW) agents has increased significantly both abroad and at home due to the availability of information and large quantities of industrial chemicals. This growing threat requires new techniques and technologies for high s ...

In recent years, the military has been integrating robotic systems into tasks previously performed entirely manually by soldiers. Examples include explosive ordnance disposal (EOD), surveillance and reconnaissance, urban search and rescue (USAR), chemical, biological, and nuclear (CBN) operations, and medical assistance and evacuation. A typical application is for a soldier (remote operator) to te ...

There is a critical need for lighter, smaller, inexpensive, and higher performance optical components in many military programs such as Thermal Weapon Sight (TWS), Enhanced Night Vision Goggle (ENVG), Monocular Night Vision Device (MNVD), Aviators Night Vision Imaging System (ANVIS), Sniper Night Sight (SNS), Clip-on Sniper Night Sight, and Lightweight Laser Designator Rangefinder (LLDR). Precisio ...

The Helios Remote Sensing Systems team will develop a miniature, low power, 360-degree field of view Moving Target Indicator (MTI) radar sensor prototype that will alert the soldier to the whereabouts of targets out to at least 25 meters with a goal of 50 meters while operating in harsh environments. The sensor prototype will be mounted, embedded, and integrated within the Advanced Combat Helmet a ...

Venezuelan equine encephalitis virus causes an acute debilitating disease in humans characterized by fever, mylagia, headache, lymphopenia and malaise and can also lead to neurological symptoms and encephalitis. The highly pathogenic strains are frequently associated with epidemics in North Central and South America and VEEV is classified as a category B select agent. Vaccines against VEEV have be ...

Universal Serial Bus (USB) devices such as thumb drives are commonly used to share information between computers. These innocuous-looking devices, however convenient, also serve as vectors for attacks. For example, unsuspecting military personnel can easily carry malicious software or hardware into secure environments via USB thumb drives. Malicious USB devices present a significant risk to users, ...

Addition of hydrogen/syngas to a compression engine has shown to improve engine efficiency and emissions. While this has been studied in detail with diesel engines, little has been done to determine its effects on an engine operating on JP-8. There are also several inconsistencies in published reports regarding the effects of H2 injection that need to be addressed. With advancements in fuel reform ...