Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. 3D Tip Characterization and Surface Reconstruction

    SBC: Nanometrology International, Inc.            Topic: 9070168TT

    Nanometrology International, Inc. (NMI) proposes to demonstrate the feasibility of 3-dimensional (3D) characterization of nanoscale objects using scanning probe microscopy (SPM) with a measurement uncertainty of less than 0.7 nm. To accomplish this task, we propose a novel method of 3D tip characterization and use of an innovative surface reconstruction algorithm recently introduced by NIST and th ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  2. A compact dose delivery system for proton radiation therapy

    SBC: PROCURE TREATMENT CENTERS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): In comparison to standard x-ray therapy, proton therapy allows an increased dose of radiation to a tumor and by reducing the amount of radiation to healthy tissue. As a result, it provides the best possible option for using radiation to control and eliminate tumors with the least short and long term toxic side effects. Currently less than 1% of all radiation th ...

    SBIR Phase II 2011 Department of Health and Human Services
  3. A High Efficiency Corticosteroid Dry Powder Inhaler for Pediatric Use

    SBC: SAVARA INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Asthma is a chronic respiratory disease with a global human and economic burden on patients, and society. Asthma treatment mainly consists of inhaled corticosteroids and bronchodilators, which enable adult populations to function well despite the disease. Small airway inflammation is particularly important in the pathogenesis of asthma in children, and hence th ...

    SBIR Phase I 2011 Department of Health and Human Services
  4. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. A Hybrid Venous Cardiotomy Reservoir

    SBC: CIRCULATORY TECHNOLOGY INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): The cardiopulmonary bypass circuit (i.e. the Heart Lung Machine) that supports patients undergoing cardiac surgery, is constantly being refined. Both the venous reservoir and the cardiotomy reservoir, prominent in the cardiopulmonary bypass circuit have weakness. Phase II SBIR funding allowed us to develop a Hybrid venous reservoir that (1) is superior in air h ...

    SBIR Phase II 2011 Department of Health and Human Services
  6. A NEW METHOD FOR THE ANALYSIS OF VITAMIN D

    SBC: NOVILYTIC, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): After almost a century of research there are still critical questions regarding the role of vitamin D in health and disease. Beyond the well established function of vitamin D in bone health, evidence is emerging that itmay be a risk factor in chronic diseases ranging from autoimmune diseases and cancer to cardiovascular disease and type II diabetes. One complic ...

    SBIR Phase I 2011 Department of Health and Human Services
  7. A new technology for functional solubilization of kinases

    SBC: Molecular Kinetics Inc            Topic: NIGMS

    DESCRIPTION (provided by applicant): Protein kinases are essential enzymes that function primarily as components of signaling pathways, regulating cellular responses such as division, growth, differentiation, and death. Abnormalities in these signaling pathways can lead to wide- ranging and devastating pathological conditions. For these reasons, protein kinases are important targets for drug devel ...

    SBIR Phase II 2011 Department of Health and Human Services
  8. A Novel, Inexpensive Cryopreservation System for Stable-80 degree C Storage of A

    SBC: GENERAL BIOTECHNOLOGY, LLC            Topic: NCRR

    DESCRIPTION (provided by applicant): The overall goal of this proposal is to design and develop a type of cryopreservation media and an easy-to-use cooling device that allow the long-term storage and safe shipment of animal model germplasm (embryos and spermatozoa) and embryonic stem cells (ESCs) at -80oC. Storage and maintenance of valuable genotypes of animal model species as live animal lines w ...

    SBIR Phase I 2011 Department of Health and Human Services
  9. A Patient-Initiated, Multilingual Request Conveyance System

    SBC: Transcendent International, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): The aim of this project is to develop a multilingual software application designed for use on a touchscreen tablet device placed at the bedside that allows hospitalized patients with limited English proficiency (LEP) tocommunicate frequently encountered patient requests to their English-speaking providers. Given the current paucity of linguistically appropriate ...

    SBIR Phase II 2011 Department of Health and Human Services
  10. A universal influenza vaccine by dual-domain fusion with a novel carrier protein

    SBC: KJ Biosciences LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): The rapid genetic changes of influenza viruses continue to cause great difficulties with current strain- specific influenza vaccines in providing adequate control for influenza epidemics and effective countermeasures against pandemics. Thus, a universal vaccine that targets conserved antigen domains and provides protection against all influenza virus strains is ...

    SBIR Phase I 2011 Department of Health and Human Services
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