Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. 3D Microfluidic Platform for in vitro Hematopoietic Stem Cell (HSC) Culture

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD10103

    Poor drug candidates are often identified late in the drug development process (e.g., in the preclinical and clinical phases) and contribute significantly to the high cost and low yield of drug discovery. As a result, new tools are needed to accelerate the assessment of drug candidate toxicity earlier in the drug development process. To address this Chemical/Bio Defense (CBD) need, Physical Optics ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  2. 3D Tip Characterization and Surface Reconstruction

    SBC: Nanometrology International, Inc.            Topic: 9070168TT

    Nanometrology International, Inc. (NMI) proposes to demonstrate the feasibility of 3-dimensional (3D) characterization of nanoscale objects using scanning probe microscopy (SPM) with a measurement uncertainty of less than 0.7 nm. To accomplish this task, we propose a novel method of 3D tip characterization and use of an innovative surface reconstruction algorithm recently introduced by NIST and th ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  3. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  4. Advanced Transmitter for Chem-Bio Standoff Detection

    SBC: DBC Technology Corp.            Topic: CBD11106

    Program tasks include analysis to improve wavelength diversity, high PRF discharges and catalysis in normal and isotopic pulsed CO2 laser mixtures, and high energy extraction in a single mode resonator. Analysis will be performed for pulse energy scaleup to the 1-5 J level at high PRF in support of the cloud search, track, and map functions. The impact of improved laser operation and enhanced da ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. Analysis of New WWVB Modulation Schemes for Future Broadcast

    SBC: XW, LLC dba Xtendwave            Topic: N/A

    This Phase 2 project targets the completion of the development of an improved system for the broadcasting of the WWVB signal, as a direct continuation of the Phase 1 project, which successfully validated the proposed approach through a feasibility study and analyses. Objectives of this project include the design of the new modulation scheme and protocol, the development of a new time-code generato ...

    SBIR Phase II 2011 Department of CommerceNational Institute of Standards and Technology
  6. Development of an in vitro assay as correlate of passive immune protection against botulinum neurotoxin to minimize use of whole animal testing

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: CBD11109

    This Small Business Innovation Research Phase I project will develop a non-animal based in-vitro assay for determining the efficacy of Botulinum (BoNT) neutralizing therapeutics; the dual nanopore assay (DNPA). New technologies are currently needed in order to facilitate the development and approval of BoNT vaccines and therapies, and align with the NIH and FDA"s guidance for reducing/replacing th ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  7. Environmental Chambers for and Integrating Sphere-based Weathering Device

    SBC: Measurement Analysis Corporation            Topic: 9060173TT

    Using a new concept for humidity control, based on a proprietary saturated air source, MAC will develop a design for an environmental chamber for use with NIST’s SPHERE UV source, in weathering or other UV degradation studies. The chamber will interface to the exit port of the SPHERE, maintaining the material coupons, mounted in a standardized sample holder, at a programmed temperature and relat ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  8. HF Radar Calibration with Automatic Identification System Ships of Opportunity

    SBC: CODAR OCEAN SENSORS, LTD            Topic: 841

    Over 300 HF RADARs worldwide are producing ocean surface data that is used in oil spill response, search & rescue, vessel traffic management, and research. In the U.S. there are 100+ systems supplying real-time data to the Coast Guard, NOAA IOOS, OR&R and other operational groups. To provide the highest quality data to stakeholders, systems should be calibrated by measuring the receive antenna p ...

    SBIR Phase II 2011 Department of CommerceNational Oceanic and Atmospheric Administration
  9. Improved M8 Test Paper for Chemical Agent Detection

    SBC: Intelligent Optical Systems, Inc.            Topic: CBD11103

    Intelligent Optical Systems (IOS) proposes to develop a field-rugged, colorimetric indicating test paper that is capable of detecting multiple chemical warfare agents (CWAs), at low concentrations, in adverse environments. The proposed sensor array will detect threatening chemical agents and provide a visual readout after coming in contact with the agent, or agents. This array will overcome the st ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  10. Interferometric Angle Measurement

    SBC: Optical Physics Company            Topic: 9060263R

    Optical Physics Company is proposing to implement an interferometric angle sensor for the purpose of determining the relative angle between the two diffracting crystals. Two approaches can be pursued, namely (1) the dual grating interferometer, and (2) the angle interferometer. The estimated cost of materials for building the angle sensor in quantity ranges between $2K and $12K. The expected accur ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
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