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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  2. Analysis of New WWVB Modulation Schemes for Future Broadcast

    SBC: XW, LLC dba Xtendwave            Topic: N/A

    This Phase 2 project targets the completion of the development of an improved system for the broadcasting of the WWVB signal, as a direct continuation of the Phase 1 project, which successfully validated the proposed approach through a feasibility study and analyses. Objectives of this project include the design of the new modulation scheme and protocol, the development of a new time-code generato ...

    SBIR Phase II 2011 Department of CommerceNational Institute of Standards and Technology
  3. Aptamer-Enhanced Biorecognition Reagent System

    SBC: OMNISITE BIODIAGNOSTICS, INC.            Topic: N/A

    "OmniSite BioDiagnostics, Inc. (OmniSite) proposes to develop DNA Aptamers to Bacillus anthracis (nonpathogenic Sterne strain) spores and staphylococcal enterotoxin B (SEB) by the SELEX process. Aptamers are less expensive than antibodies to produce, do notrequire animal hosts for production, can be protected from nucleases, and used in a variety of assay formats to replace antibodies. In Phase I, ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
  4. Automated Preferential Display for the Analysis of Gene Expression Profiles

    SBC: GENEXPRESS INFORMATICS, INC.            Topic: N/A

    "GeneXpress Informatics, Inc. (GXI) and Dr. James P. Chambers of UTSA propose to develop a revolutionary differential gene display technology, called Preferential Display (PD) which will provide for a simplified, cost-effective method to identify thesegenes for use in discovering gene expression profiles without having any prior knowledge of an organism, tissue or biological samples' genome. The ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
  5. Development of Array-Based Universal Biosensing Devices Based Upon Intelligent Oligonucleotide Probe Sets

    SBC: Vitruvius Biosciences            Topic: N/A

    "The present proposal describes strategies leading to the development of an array-based universal biosensor for detecting and differentiating microbial species, or differentiating at the DNA or RNA level between cell types of the same species. The proposed strategy relies on the differential hybridization of genomic DNA, extrachromosomal DNA, mRNA, or ribosomal RNA from different sources to a comm ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
  6. 3D Tip Characterization and Surface Reconstruction

    SBC: Nanometrology International, Inc.            Topic: 9070168TT

    Nanometrology International, Inc. (NMI) proposes to demonstrate the feasibility of 3-dimensional (3D) characterization of nanoscale objects using scanning probe microscopy (SPM) with a measurement uncertainty of less than 0.7 nm. To accomplish this task, we propose a novel method of 3D tip characterization and use of an innovative surface reconstruction algorithm recently introduced by NIST and th ...

    SBIR Phase I 2011 Department of CommerceNational Institute of Standards and Technology
  7. Miniaturized Real-time Visible/UV Spectrometer

    SBC: Spectronix Systems, Inc.            Topic: N/A

    "The miniaturized spectrometer presented in this proposal is a simple hand-held static Fourier-transform spectrometer for real-time detection and characterization of chemicals in rapidly changing and/or fast moving environments such as chemicals in cloudsand vapor. The core of the system consists of a pair of mirrors and a line scan CCD array. The interferogram is generated in the spatial domain a ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
  8. Modular Environmental Situational Awareness Technology

    SBC: TECHSHOT, INC.            Topic: N/A

    "This proposal addresses the activities associated with the development of the Modular Environmental Situational Awareness Technology (MESAT), which is intended as an important part of the United States' response to a terrorist attack using chemical orbiological weapons of mass destruction. The MESAT will be a suite of environmental, meteorological, geographic, and seismic sensors incorporated int ...

    SBIR Phase I 2002 Department of DefenseOffice for Chemical and Biological Defense
  9. Multiplex Microsphere Assay for Botulinum Neutralizing Antibodies

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD11109

    Currently, the accepted standard experimental model for measuring protective efficacy against botulism is the Mouse Lethality Neutralization (MLN) assay. Botulism poisoning is a life threatening condition that is not only a public health concern, but could also be a potential biological weapon. With seven serotypes of botulinum neurotoxins, there is need for an alternative to the MLN assay due t ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  10. Narrowband Perfect Absorber using Metamaterials

    SBC: Phoebus Optoelectronics LLC            Topic: CBD11102

    We propose a metamaterial-enhanced microbolometer with strong absorption over a narrow band that is dynamically tunable over the 8-10 micron band. A single-layer photonic metamaterial consisting of a thin metal film perforated with a 2-D array of dielectric apertures will be deposited on an amorphous-Silicon layer acting as an absorber and bolometer. The metamaterial, in conjunction with planar di ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
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