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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A compact dose delivery system for proton radiation therapy


    DESCRIPTION (provided by applicant): In comparison to standard x-ray therapy, proton therapy allows an increased dose of radiation to a tumor and by reducing the amount of radiation to healthy tissue. As a result, it provides the best possible option for using radiation to control and eliminate tumors with the least short and long term toxic side effects. Currently less than 1% of all radiation th ...

    SBIR Phase II 2011 Department of Health and Human Services
  2. A High Efficiency Corticosteroid Dry Powder Inhaler for Pediatric Use

    SBC: SAVARA INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Asthma is a chronic respiratory disease with a global human and economic burden on patients, and society. Asthma treatment mainly consists of inhaled corticosteroids and bronchodilators, which enable adult populations to function well despite the disease. Small airway inflammation is particularly important in the pathogenesis of asthma in children, and hence th ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. A Hybrid Venous Cardiotomy Reservoir


    DESCRIPTION (provided by applicant): The cardiopulmonary bypass circuit (i.e. the Heart Lung Machine) that supports patients undergoing cardiac surgery, is constantly being refined. Both the venous reservoir and the cardiotomy reservoir, prominent in the cardiopulmonary bypass circuit have weakness. Phase II SBIR funding allowed us to develop a Hybrid venous reservoir that (1) is superior in air h ...

    SBIR Phase II 2011 Department of Health and Human Services
  4. Air Barrier System to reduce contamination of wounds during surgery

    SBC: NIMBIC SYSTEMS, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): (Note: All resubmission updates in this proposal are designated by italics) This Small Business Innovation Research (SBIR) Phase II project is an evaluation of a novel device designed to reduce the risk of surgical site infection, the Air Barrier System , during a pilot clinical trial. The Air Barrier System, shown during SBIR Phase I study to reduce the presen ...

    SBIR Phase II 2011 Department of Health and Human Services
  5. Analysis of New WWVB Modulation Schemes for Future Broadcast

    SBC: XW, LLC dba Xtendwave            Topic: N/A

    This Phase 2 project targets the completion of the development of an improved system for the broadcasting of the WWVB signal, as a direct continuation of the Phase 1 project, which successfully validated the proposed approach through a feasibility study and analyses. Objectives of this project include the design of the new modulation scheme and protocol, the development of a new time-code generato ...

    SBIR Phase II 2011 Department of CommerceNational Institute of Standards and Technology

    SBC: NOVILYTIC, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): After almost a century of research there are still critical questions regarding the role of vitamin D in health and disease. Beyond the well established function of vitamin D in bone health, evidence is emerging that itmay be a risk factor in chronic diseases ranging from autoimmune diseases and cancer to cardiovascular disease and type II diabetes. One complic ...

    SBIR Phase I 2011 Department of Health and Human Services
  7. A new technology for functional solubilization of kinases

    SBC: Molecular Kinetics Inc            Topic: NIGMS

    DESCRIPTION (provided by applicant): Protein kinases are essential enzymes that function primarily as components of signaling pathways, regulating cellular responses such as division, growth, differentiation, and death. Abnormalities in these signaling pathways can lead to wide- ranging and devastating pathological conditions. For these reasons, protein kinases are important targets for drug devel ...

    SBIR Phase II 2011 Department of Health and Human Services
  8. An Interactive Text Messaging Intervention to Improve Drug Court Outcomes


    DESCRIPTION (provided by applicant): Drug Courts reflect the cutting edge of new, innovative treatments for substance abuse. A text messaging system integrated as part of the Drug Court's treatment program holds the promise of improving treatment outcomesand has positive market potential. Shorter, less-costly, more effective treatment may be possible with the addition of a telephone texting s ...

    SBIR Phase I 2011 Department of Health and Human Services
  9. An Open Source Digital Pathology System Supporting Multi-Touch Interaction

    SBC: Kitware, Inc.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Medical records are being digitized in order to improve patient care, and the integrated digitization of all components of the medical record will also help reduce the number of errors and reduce health care costs. Images form part of the medical record. In some specialty areas such as radiology, the use of digital imaging is widespread. However, in other speci ...

    SBIR Phase I 2011 Department of Health and Human Services
  10. A Novel, Inexpensive Cryopreservation System for Stable-80 degree C Storage of A


    DESCRIPTION (provided by applicant): The overall goal of this proposal is to design and develop a type of cryopreservation media and an easy-to-use cooling device that allow the long-term storage and safe shipment of animal model germplasm (embryos and spermatozoa) and embryonic stem cells (ESCs) at -80oC. Storage and maintenance of valuable genotypes of animal model species as live animal lines w ...

    SBIR Phase I 2011 Department of Health and Human Services
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