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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A High-Throughput Blood Esterase Panel Assay

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD10108

    Organophosphorus chemical warfare nerve agents (OP-CWA) are attractive to terrorist groups and rogue states as an inexpensive and accessible technology for chemical warfare. OP-CWA and organophosphate pesticides cause severe neurological symptoms and death by inhibiting the enzyme acetylcholinesterase (AChE); the resulting excess acetylcholine accumulates and overstimulates the human or animal bo ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  2. Direct Electrochemical Biowarfare Sensor

    SBC: Fractal Systems, Inc.            Topic: DTRA03008

    The proposed Phase II SBIR program is dedicated to the creation and testing of a multispecific DNA biowarfare sensor based on ultrathin oligonucleotide-modified conducting polymer films. Based on the reagent-free sensor prototype developed in Phase I, wh

    SBIR Phase II 2004 Department of DefenseOffice for Chemical and Biological Defense
  3. Magnetic Concentrator & Cartridge System to Enhance Food Safety

    SBC: Operational Techologies Corporation            Topic: CBD04108

    Foodborne pathogen detection has always been faced with volume and matrix problems, i.e., low numbers of viral or bacterial pathogens in a large volume of solid or liquid foods that are still potentially infectious. Despite sensitive techniques such as PCR and immunomagnetic-electrochemiluminescence (IM-ECL), there still exists a need to concentrate and semi-purify pathogens from large (liter) vo ...

    SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense
  4. Multiplex Microsphere Assay for Botulinum Neutralizing Antibodies

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD11109

    Currently, the accepted standard experimental model for measuring protective efficacy against botulism is the Mouse Lethality Neutralization (MLN) assay. Botulism poisoning is a life threatening condition that is not only a public health concern, but could also be a potential biological weapon. With seven serotypes of botulinum neurotoxins, there is need for an alternative to the MLN assay due t ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  5. Nanoalumina Water Filtration System

    SBC: ARGONIDE CORPORATION, THE            Topic: CBD04304

    A miniature, transportable filter system is required for warfighters when traditional resupply is unavailable. The desired technology would remove both chemical and biological agents. A device that integrates sensing capability to actuate the purification system is also desired. We developed a non-woven filter using a nano alumina fiber only 2 nanometers in diameter. It is capable of > 99.9999 ...

    SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense
  6. Narrowband Perfect Absorber using Metamaterials

    SBC: PHOEBUS OPTOELECTRONICS LLC            Topic: CBD11102

    We propose a metamaterial-enhanced microbolometer with strong absorption over a narrow band that is dynamically tunable over the 8-10 micron band. A single-layer photonic metamaterial consisting of a thin metal film perforated with a 2-D array of dielectric apertures will be deposited on an amorphous-Silicon layer acting as an absorber and bolometer. The metamaterial, in conjunction with planar di ...

    SBIR Phase I 2011 Department of DefenseOffice for Chemical and Biological Defense
  7. No Power Detection and Identification of Nerve Agents

    SBC: LYNNTECH INC.            Topic: CBD10101

    Identification of organophosphates (OPs) based nerve agents, is vital to the protection of U.S. armed forces personnel. Existing detection methods use bulky and expensive laboratory equipment, negating their battlefield use. Colorimetric indicators such as the currently deployed M8 and M9 detection papers are the fastest, cheapest, and easiest type of detector to use; however, these cannot detect ...

    SBIR Phase II 2011 Department of DefenseOffice for Chemical and Biological Defense
  8. Portable System for Sample Preparation and Differentiation of Pathogens at Strain Level

    SBC: LYNNTECH INC.            Topic: CBD04107

    During the anthrax attacks in 2001, investigators had difficulty in differentiating the strains apart because B. anthracis has a low level of genetic variability. This event demonstrated the need for rapid and precise molecular subtyping technologies. Lynntech proposes to develop an ultra-sensitive quantum dots-based molecular beacon fluorogenic reporter system to identify the presence of specif ...

    SBIR Phase I 2004 Department of DefenseOffice for Chemical and Biological Defense
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