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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Bottom Feeder- A Highly Maneuverable Autonomous Underwater Vehicle

    SBC: Tridentis Advanced Marine Vehicles LLC            Topic: 822

    The Bottom Feeder project is designed to prove out the research done in Phase I using a prototype platform. The prototype will be a full size version of the platform designed during Phase I. The Phase I platform was designed to work in two operational configurations, a highly efficient mode and a highly maneuverable mode, with the ability to switch between them while submerged. The platform is equ ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  2. Improving Spatiotemporal Precision in Noninvasive Electrical Neuromodulation

    SBC: Brain Electrophysiology Laboratory Company, LLC            Topic: 101

    This application describes the commercialization of the Geodesic Transcranial Electrical NeuromodulationGTENtechnology to achieve noninvasive neuromodulation with improved spatiotemporal precisionThe GTEN system enables both EEG source analysis and configurable electrical neuromodulation with theelectrodes of the Geodesic Sensor NetNow in beta release to selected research customersthe GTEN technol ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Novel Compounds for Treatment of Heart Arrhythmias in CPVT

    SBC: Elex Biotech, Inc            Topic: NHLBI

    PROJECT SUMMARY The goal of this project is to complete the preclinical development of Elex Biotechandapos s novel compounds that target and treat the underlying molecular cause of catecholaminergic polymorphic ventricular tachycardiaCPVTCPVTThere are no FDA approved treatments for CPVTa rare genetic disorder affectingindividualswith typical onset in childrenyears of age and no reported difference ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. A Single-Cell Proteomic instrument for Predictive Product Quality Check in Autologous CAR-T Immunotherapies

    SBC: IsoPlexis            Topic: NCI

    While CAR T therapies have advanced in the clinicthere are still two specific issues using these breakthrough therapies for blood cancersDurable responses in patients are only atand Cytokine Release Syndrome occurs inof treated patientsThese limitationsfor a drug that costs as much as $may cost an additional $for treating adverse events leading to caution for many clinical centers to administer th ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Mindfulness Mobile App to Reduce Adolescent Substance Use

    SBC: Oregon Research Behavioral Intervention Strategies, INC            Topic: NIDA

    Abstract Adolescents in the juvenile justice system demonstrate very high rates of tobaccoalcoholand other drug useATODwith rates that are estimated to be three times higher than non justice involved youthSubstanceabusing youthespecially those who are involved in the juvenile justice systemare at higher risk than nonusers for mental health problemsincluding depressionconduct problemspersonality di ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. HLS-Affordable, quantitative microchip-electrophoresis for sickle cell disease screening

    SBC: Hemex Health, Inc.            Topic: NHLBI

    PROJECT SUMMARY Sickle Cell DiseaseSCDaffectsAmericans and more thanmillion people globallyprimarily in economically disadvantaged populationsIt is estimated that nearlyof children born with SCD in these areas die before the age of fivealthoughcould be saved through simplecost effective treatments if diagnosed early according to World Health OrganizationEarly diagnosis of SCD remains a challenge i ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Culturally Responsive Stress Reduction: A Mobile Mindfulness Application toSupport Health Promotion for African Americans

    SBC: IRIS MEDIA INC            Topic: 102

    ABSTRACTThe proposed interventionCulturally Responsible Stress ReductionA Mobile Mindfulness Application to Support Health Promotion for African AmericansCRSRis designed to encourage the use of mindfulness to mitigate the disproportionate amount of stress related health disparities facing African AmericansCurrent mindfulness approaches have been unsuccessful in engaging this populationThis proposa ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Multi-Omic Single-Cell System for Improved Combination Cancer Immunotherapy Monitoring and Implementation

    SBC: IsoPlexis            Topic: 102

    IsoPlexis proposes to deliver a novel multi omic method for targeted profiling of both the TCR sequence and proteome from an array ofsingle cellsSpecificallywe will deliver a single cellTCR sequencing and protein capture assay for identifying responsive antigen specific TCRsand concurrently evaluate these T cells for functional response to that antigenThe challenge remains to link the activation o ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Cross-Protective Multivalent Vaccine for Tick-Borne Flaviviruses

    SBC: Hawaii Biotech, Inc.            Topic: NIAID

    Project Summary AbstractThe NIH NIAIDStrategic Plan is specifically directed at promoting research that can provide solutions to mitigate the threat posed by emerging and re emerging diseasesThe tick borne flavivirusTBFVgroup includes a number of important human pathogens that result in serious neurological or hemorrhagic diseases that are either Category B or C priority pathogensThe TBFVs are con ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Localized Delivery of Sirolimus to Hemodialysis Vascular Access Grafts

    SBC: Cylerus, Inc.            Topic: NIA

    Abstract CylerusIncis developing an implantablesirolimus eluting cuff and reservoir systemcombined with a clinically approved drug pumpto solve the difficult problem of prosthetic vascular graft failureVascular grafts constructed using either synthetic polymers or native veins are widely used in vascular surgeryThe most common indications for these grafts areHemodialysis accessin which blood acces ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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