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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Medicare Information Resource Center (MIReC)

    SBC: Acumen, LLC            Topic: N/A

    The purpose of the project is to facilitate the acquisition and linking of data from the Centers for Medicare and Medicare Services (CMS) to participants of surveys and registries sponsored by NIA and relate federal agencies, and to promote the use of these data for research and public policy. The intent is to create an infrastructure that will reduce the expense and time required to obtain, creat ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  2. High-resolution tomography for small animal imaging

    SBC: ADELPHI TECHNOLOGY INC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this proposal is to develop a nanometer-scale resolution computerized tomographic imaging system for small animal and molecular imaging. This will be achieved by building a system designed to work with x-ray compound refractive lenses. Research and development efforts will concentrate on the x-ray source, lens and detector as well as the constructi ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Validation of Apnea Risk Evaluation System Sleep Scoring

    SBC: ADVANCED BRAIN MONITORING, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Obstructive Sleep Apnea (OSA) is the most common disorder observed in the practice of sleep medicine and is responsible for more mortality and morbidity than any other sleep disorder. OSA causes daytime drowsiness, and has been associated with hypertension, increased risk of congestive heart failure, coronary artery disease, myocardial infarction, cardiac arrhy ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Nanoliter Lab-on-a-chip for Protein Crystallization

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The human genome contains at least 30,000 unique open reading frames that may yield >100,000 polypeptide products. These products assemble into more than a million biologically relevant structures or proteins of interest per organism. Crystallization and X-ray diffraction of these proteins is routinely performed to determine their 3D structure which needs to be ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Nanoliter Lab-on-a-Chip for Blood Diagnostics

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Latrogenic blood loss or "bleeding into the laboratory" is an important reason for administration of small volume transfusions in very low birth weight premature 6infants. A direct correlation was found between the volume of blood drawn for diagnostics and subsequent volume transfused. In neonatal infants, there may not be enough collected blood sample to perfo ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Improved Orthopedic Implant Surface Coatings

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Many contemporary medical and dental therapies include the replacement or repair of tissues using materials such as metal. Currently there are at least 150,000 hip replacements, 300,000 knee replacements, and 500,000 dental implant procedures performed in the US each year (Kurtz, Mowat et al. 2005). These numbers are expected to increase as the baby boom gen ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Multiplexed Protein Measurement by Real-time Immuno-PCR

    SBC: AMPLIFIED PROTEOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Numerous proteomics platforms for measuring multiple proteins in parallel have been developed, but adoption has been limited by the fact that they all are orders of magnitude less sensitive than standard ELISA assays. By contrast, methods for quantitatively measuring the levels of multiple mRNAs in parallel are very robust and sensitive. The real-time polymera ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  8. A New Topical Antiandrogen Benefits Acne Treatment

    SBC: ANDROSCIENCE CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Acne is the second most expensive skin disease, resulting in $2.23 billion in medical spending annually. Although the overall health is not impaired, acne can produce cutaneous and emotional scars that last a lifetime. It is not surprising that there is high willingness to pay for acne treatment, and the market is expected to grow to $12 billion. Currently, ava ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Orthotopic models of tumor angiogenesis and blood flow

    SBC: ANTICANCER, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a need for clinically-relevant imageable animal models of tumor blood flow, intravascular cancer-cell trafficking and extravasation, critical targets for current drug evaluation and development. Most models of tumor cell trafficking and blood flow are either based on subcutaneous transplantation of tumors or dorsal skin- fold window models. These model ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Dual-color tumor-host imaging models

    SBC: ANTICANCER, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II application will further develop dual-color imageable tumor-host-interaction nude mouse models, developed in the Phase I application, to be used in Phase III to discover and evaluate new effective agents for stromal therapy, including angiogenesis. The host models are the ubiquitously-expressing green fluorescent protein (GFP)-nude mouse with GFP ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
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