Award Data

We propose to continue the development and characterization of a polymeric nanoencapsulation technology that can increase the lifetime of a protein therapeutic agent within a biological system. The materials have been demonstrated to exhibit no cytotoxicity and to efficiently deliver antibody against Protective Antigen of bacillus anthracis.

We propose that a comparative colorimetric assay be developed that will use a ticket of the same dimensions as the current ANP immunoassay tickets. This will allow the AChE test to be conducted using a similar workflow as the lateral flow immunoassay-based HHAs and be similarly read on the ANP reader to yield an unambiguous result independent of user judgment.

Low-light-level photodetector arrays are proposed for detecting the weak optical emission spectra from the trace atoms in the laser-induced breakdown spectroscopy (LIBS). The proposed semiconductor image intensifier and low-light-level camera utilize the miniaturized and monolithically integrated version of a proven solid-state detector technology, and is expected to be able to detect femto-watts ...

The objective of this proposal is to improve the computational tools identified in Phase 1 that will be useful in assessing rocket and missile propulsion systems for compliance with insensitive munitions (IM) requirements. Comprehensive testing to ascertain IM compliance for such systems is time-consuming and expensive. High-fidelity computational tools exist that can be used to address the asse ...

The Phase 2 objective is to provide NIST with a modular gauge head unit equipped with InsituTec's standing wave probe technology. The complete gauge head unit will be retrofitted to the NIST M48 which is one of the most precise measuring machines in the world. This unit will enable NIST to achieve the agency's program goal in dimensional metrology which is to provide microscale measurement capacit ...

Plant chloroplasts are capable of producing significant quantities of high quality bioengineered proteins with biomedical applications. Improving the commercial supply of diagnostic antigens and vaccines through use of our pliable expression platform will provide an important technological advance compared with the current mammalian and microbial cell culture platforms. Our innovative approach c ...

Preservation of the perishable food, especially fresh fruits and vegetables (FF&V), is particularly challenging due to substantial amount of refrigeration required to prevent spoilage. In the case of FF&V, the refrigerated air can quickly become contaminated with ethylene gas produced by the fruits and vegetables, which can lead to autocatalytic ripening of FF&V and accelerate spoilage even at id ...

We propose Ranger ES, a low cost, autonomous underwater vehicle (AUV) for three-dimensional profiling and water samplings of chemical, physical, and biological parameters of oceanic and fresh waters. The AUV will be programmable by point and click to analyze a volume of water continuously for the selected parameters. After returning for pickup after a day¿s run, it will download its data into a ...

This Phase II proposal presents the design and development approach for a distributed Doppler-radar network system for sense-through-the-wall intelligence collection. Phase I research successfully demonstrated the proof of concept and yielded a viable path of development that will culminate in the delivery of a working prototype system that is covert, robust, and capable of detecting multiple sta ...

In response to Army topic A052-080-1968, Oceanit Laboratories has proposed the Hostile Fire Detection System (HFDS), which will detect attacks from close range weapons and locate enemy combatants. HFDS is based on Oceanit’s patented MOST focal plane. It utilizes a time-intensity identification technique that rapidly detects weapons fire and rejects false signals such as sun glint. HFDS is config ...